Duman Ozgür, Koyun Mustafa, Akman Sema, Güven Ayfer Gür, Haspolat Senay
Department of Pediatric Neurology, School of Medicine, Akdeniz University, Antalya, Turkey.
J Child Neurol. 2006 Mar;21(3):255-6. doi: 10.2310/7010.2006.00049.
Hypokalemic periodic paralysis can occur secondarily to excessive potassium loss. Thyrotoxicosis, diuretic ingestions, hyperaldosteronism, barium poisoning, Gitelman syndrome, and Bartter syndrome are among the disorders causing secondary hypokalemic periodic paralysis. Clinical presentation of Bartter syndrome with hypokalemic periodic paralysis is rare. A 12-year-old boy was admitted to our hospital because of transient paralysis. He had been suffering from transient weakness attacks for 2 years and had had a total of 10 attacks, lasting 1 to 3 days. He had growth retardation, polyuria, and polydipsia. Laboratory examinations revealed hypokalemic alkalosis, normomagnesemia, hypercalciuria, and hyperaldosteronism. The clinical and laboratory findings were in accordance with Bartter syndrome. He has been followed up for 6 months and has suffered no further paralytic attacks under indomethacin therapy. This case highlights the importance of blood pH measurement in patients with hypokalemic periodic paralysis; it might prevent misdiagnosis and mismanagement in such diseases.
低钾性周期性麻痹可继发于钾过度丢失。甲状腺毒症、利尿剂摄入、醛固酮增多症、钡中毒、吉特林综合征和巴特综合征等疾病可导致继发性低钾性周期性麻痹。伴有低钾性周期性麻痹的巴特综合征临床表现罕见。一名12岁男孩因短暂性麻痹入院。他有2年的短暂性肌无力发作史，共发作10次，持续1至3天。他有生长发育迟缓、多尿和烦渴症状。实验室检查显示低钾性碱中毒、血镁正常、高钙尿症和醛固酮增多症。临床和实验室检查结果符合巴特综合征。他已接受随访6个月，在吲哚美辛治疗下未再发生麻痹发作。该病例强调了低钾性周期性麻痹患者测量血液pH值的重要性；这可能会防止此类疾病的误诊和管理不当。
