Department of Pathology (Histopathology division), Sir Ganga Ram Hospital, Rajender Nagar, New Delhi, India.
Int J Surg Pathol. 2023 Aug;31(5):791-794. doi: 10.1177/10668969221133350. Epub 2022 Nov 3.
Uterus-like mass is a rare form of endometriosis, which shows striking structural similarity to the normal uterus. Formation of a mass lesion raises clinical concern for malignancy, and pathologic examination is necessary for accurate diagnosis. We describe herein, a middle aged woman who presented with a mesenteric mass six years post hysterectomy, which was initially suspected to be a gastrointestinal stromal tumor. The resected was specimen was grossly pear shaped with microscopy showing a central endometrial glands and stroma lined cavity, surrounded by a thick muscular wall reminiscent of uterine myometrium. Histogenesis of this entity is unclear, and several theories are proposed regarding the etiology, including congenital anomaly theory, metaplasia and heterotopia theories. Our clinical scenario developed a few years after uterine morcellation, indicating a possibility of another "iatrogenic implantation" theory behind the pathogenesis of this rare lesion.
子宫样肿块是一种罕见的子宫内膜异位症形式，其结构与正常子宫惊人地相似。肿块的形成引起了对恶性肿瘤的临床关注，因此有必要进行病理检查以做出准确诊断。我们在此描述了一位中年女性，她在子宫切除术后 6 年出现肠系膜肿块，最初怀疑为胃肠道间质瘤。切除的标本大体上呈梨形，镜下显示中央子宫内膜腺体和基质排列的腔，周围有厚厚的肌肉壁，类似于子宫子宫肌层。该实体的组织发生尚不清楚，关于其病因提出了几种理论，包括先天性异常理论、化生和异位理论。我们的临床情况在子宫分碎术几年后出现，表明这种罕见病变的发病机制背后可能存在另一种“医源性种植”理论。
