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非酒精性脂肪性肝炎诊断——一种基于模型的个性化医学方法。

Nonalcoholic Steatohepatitis Diagnosis - A Model-Related Personalized Medicine Approach.

机构信息

Inserm URMS 1142, Sorbonne University, Paris- France.

Public Health Departement, North-East Parisian Hospitals, France.

出版信息

Stud Health Technol Inform. 2022 Nov 3;299:191-195. doi: 10.3233/SHTI220982.

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a clinical syndrome, and pathologically characterized by diffuse macro-vesicular fatty change in the hepatocytes. NAFLD includes simple nonalcoholic fatty liver disease, nonalcoholic steatohepatitis (NASH) and hepatic cirrhosis. NASH is a disease evolving under the influence of various stimuli still poorly understood, but where insulin resistance is prominently. In this paper, we present a new diagnosis model to predict NASH.

摘要

非酒精性脂肪性肝病(NAFLD)是一种临床综合征,病理学特征为肝细胞弥漫性大泡性脂肪变。NAFLD 包括单纯性非酒精性脂肪肝、非酒精性脂肪性肝炎(NASH)和肝硬化。NASH 是一种在各种刺激因素影响下发展的疾病,其机制仍不完全清楚,但胰岛素抵抗是突出的。本文提出了一种新的 NASH 预测诊断模型。

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