抑郁对心力衰竭患者治疗依从性的影响——文献系统评价。
The Role of Depression on Treatment Adherence in Patients with Heart Failure-a Systematic Review of the Literature.
机构信息
Department of Psychology, Università Cattolica del Sacro Cuore, Milan, Italy.
Department of Psychology, Harvard University, Cambridge, MA, USA.
出版信息
Curr Cardiol Rep. 2022 Dec;24(12):1995-2008. doi: 10.1007/s11886-022-01815-0. Epub 2022 Nov 3.
INTRODUCTION
Although poor medication adherence is considered an impacting risk factor for worsening heart failure (HF) outcomes, adherence rates in HF patients continue to be considerably low. To improve this condition, several studies investigated the impact of many determinants on medication adherence; however, few authors explored the role of depression on it.
PURPOSE OF REVIEW
The purpose of this systematic review was to explore the association between depressive symptoms and medication adherence in HF patients. In particular, the research question was is depression a barrier to medication adherence in HF patients?
METHODS
A systematic review of quantitative analysis studies was undertaken. Six electronic databases were searched between the end of October and March 2022. Thirty-one trials were included, all of them assessed depression, adherence to medication, and their possible relationship.
RESULTS
As was intended, findings showed that the impact of a mild to moderate level of depression was significant on adherence to treatment in HF patients. However, many other risk factors emerged, like family support and health practices (es. low sodium diet).
CONCLUSION
The detection of depression in the setting of HF should be crucial to HF patients' physical health and quality of life. Future research should take depression into account, exploring this area through self-report and qualitative interview as well.
简介
尽管药物治疗依从性差被认为是导致心力衰竭（HF）恶化的影响因素之一，但 HF 患者的治疗依从率仍然相当低。为了改善这种情况，许多研究调查了许多因素对药物治疗依从性的影响；然而，很少有作者探讨抑郁对此的影响。
目的
本系统综述的目的是探讨 HF 患者抑郁症状与药物治疗依从性之间的关系。具体来说，研究问题是抑郁是否是 HF 患者药物治疗依从性的障碍？
方法
对定量分析研究进行了系统回顾。在 2022 年 10 月底至 3 月期间，对六个电子数据库进行了搜索。共纳入 31 项试验，所有试验均评估了抑郁、药物治疗依从性及其可能的关系。
结果
正如预期的那样，研究结果表明，轻度至中度抑郁对 HF 患者的治疗依从性有显著影响。然而，许多其他风险因素也出现了，如家庭支持和健康行为（例如低盐饮食）。
结论
在 HF 环境中检测到抑郁应该对 HF 患者的身体健康和生活质量至关重要。未来的研究应该考虑到抑郁，通过自我报告和定性访谈来探索这一领域。
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