鸡载脂蛋白极低密度脂蛋白II（前体）信使核糖核酸的剪接途径
Splicing pathways of the chicken apo very low density lipoprotein II (pre)messenger RNA.
作者信息
Noteborn M, Arnberg A, de Jonge M, Ab G, Gruber M
出版信息
FEBS Lett. 1986 Jan 1;194(1):151-6. doi: 10.1016/0014-5793(86)80067-9.
PMID:3632793
Abstract
The precursor-mRNA transcribed from the chicken apo very low density lipoprotein II gene was identified. This gene which is under full estrogen control and only expressed in the liver, possesses three introns. Splicing intermediates were characterized by hybridization with intron-specific probes, and by electron microscopy of R-loops. The introns appear to be excised in a non-obligatory order, but at different rates.
摘要
已鉴定出从鸡载脂蛋白极低密度脂蛋白II基因转录而来的前体mRNA。该基因受雌激素完全调控，仅在肝脏中表达，含有三个内含子。通过与内含子特异性探针杂交以及对R环进行电子显微镜观察，对剪接中间体进行了表征。内含子似乎以非固定顺序切除，但切除速率不同。
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