Structured Population and Health services Research Education (SPHeRE) Programme, School of Population Health, RCSI University of Medicine and Health Sciences, Mercer Street Lower, Dublin, Ireland.
Healthcare Outcome Research Centre (HORC), School of Population Health, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
BMC Health Serv Res. 2022 Nov 3;22(1):1311. doi: 10.1186/s12913-022-08657-0.
Health services research often relies on quasi-experimental study designs in the estimation of treatment effects of a policy change or an intervention. The aim of this study is to compare some of the commonly used non-experimental methods in estimating intervention effects, and to highlight their relative strengths and weaknesses. We estimate the effects of Activity-Based Funding, a hospital financing reform of Irish public hospitals, introduced in 2016.
We estimate and compare four analytical methods: Interrupted time series analysis, Difference-in-Differences, Propensity Score Matching Difference-in-Differences and the Synthetic Control method. Specifically, we focus on the comparison between the control-treatment methods and the non-control-treatment approach, interrupted time series analysis. Our empirical example evaluated the length of stay impact post hip replacement surgery, following the introduction of Activity-Based Funding in Ireland. We also contribute to the very limited research reporting the impacts of Activity-Based-Funding within the Irish context.
Interrupted time-series analysis produced statistically significant results different in interpretation, while the Difference-in-Differences, Propensity Score Matching Difference-in-Differences and Synthetic Control methods incorporating control groups, suggested no statistically significant intervention effect, on patient length of stay.
Our analysis confirms that different analytical methods for estimating intervention effects provide different assessments of the intervention effects. It is crucial that researchers employ appropriate designs which incorporate a counterfactual framework. Such methods tend to be more robust and provide a stronger basis for evidence-based policy-making.
卫生服务研究通常依赖于准实验研究设计来估计政策变化或干预措施的治疗效果。本研究旨在比较一些常用的非实验方法来估计干预效果,并强调它们各自的优缺点。我们评估了 2016 年爱尔兰公立医院实施的基于活动的资金(Activity-BasedFunding)的医院融资改革的效果。
我们估计并比较了四种分析方法:中断时间序列分析、差异中的差异、倾向评分匹配差异中的差异和合成控制方法。具体来说,我们专注于控制-治疗方法与非控制-治疗方法(中断时间序列分析)之间的比较。我们的实证例子评估了爱尔兰引入基于活动的资金后髋关节置换手术后的住院时间的影响。我们还对在爱尔兰背景下报告 Activity-Based-Funding 影响的非常有限的研究做出了贡献。
中断时间序列分析产生了在解释上存在差异的统计学显著结果,而差异中的差异、倾向评分匹配差异中的差异和纳入对照组的合成控制方法表明,患者住院时间没有统计学显著的干预效果。
我们的分析证实,用于估计干预效果的不同分析方法提供了对干预效果的不同评估。研究人员采用适当的设计来纳入反事实框架至关重要。这些方法往往更稳健,为循证决策提供了更坚实的基础。