再生障碍性贫血：近期全球儿童神秘肝炎爆发的新并发症：两例病例报告。
Aplastic anemia: a new complication in the recent mysterious hepatitis outbreak among children worldwide: two case reports.
机构信息
Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Pediatric Gastroenterology, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
J Med Case Rep. 2022 Nov 3;16(1):422. doi: 10.1186/s13256-022-03542-0.
BACKGROUND
Recently, an unknown hepatitis outbreak among children has concerned many individuals worldwide. These cases are frequently reported, mainly from Europe and other countries. In this study, we present two similar patients, who, to the best of our knowledge, are the first cases reported in the Middle East (Shiraz, Fars Province, Iran). Unlike in similar cases reported up until 30 April 2022, our patients' hepatitis eventually resulted in aplastic anemia.
CASE PRESENTATION
In this study, we present cases of two Iranian boys aged 13 and 8 years with hepatitis of unknown origin who developed aplastic anemia in the course of hospitalization.
CONCLUSIONS
Hepatitis-associated aplastic anemia is a well-known immune-mediated form of aplastic anemia that we detected in our patients and treated with immunosuppressive therapy. One patient established a satisfactory response to the treatment, but unfortunately, the other was declared brain dead.
背景
最近，儿童中出现的一种不明原因肝炎引起了全球许多人的关注。这些病例经常被报道，主要来自欧洲和其他国家。在本研究中，我们报告了两例类似的患者，据我们所知，这是首例在中东（伊朗法尔斯省设拉子）报告的病例。与截至 2022 年 4 月 30 日报告的类似病例不同，我们患者的肝炎最终导致再生障碍性贫血。
病例介绍
在本研究中，我们报告了两例伊朗男孩的病例，他们分别为 13 岁和 8 岁，患有不明原因的肝炎，在住院期间发展为再生障碍性贫血。
结论
肝炎相关性再生障碍性贫血是一种已知的免疫介导性再生障碍性贫血，我们在患者中检测到并采用免疫抑制疗法进行治疗。一名患者对治疗有满意的反应，但不幸的是，另一名患者被宣布脑死亡。
Zotero 插件