Matoq Amr, Salahuddin Asma
Department of Pediatrics, University of Florida, College of Medicine, Jacksonville, FL 32207, USA.
Department of Pediatrics, Division of Hospital Pediatrics, University of Florida, College of Medicine, Jacksonville, FL 32207, USA.
Case Rep Pediatr. 2016;2016:8648190. doi: 10.1155/2016/8648190. Epub 2016 Jun 1.
Adenoviruses are a common cause of respiratory infection, pharyngitis, and conjunctivitis in infants and young children. They are known to cause hepatitis and liver failure in immunocompromised patients; they are a rare cause of hepatitis in immunocompetent patients and have been known to cause fulminant hepatic failure. We present a 23-month-old immunocompetent infant who presented with acute noncholestatic hepatitis, hypoalbuminemia, generalized anasarca, and pancytopenia secondary to adenovirus infection.
腺病毒是婴幼儿呼吸道感染、咽炎和结膜炎的常见病因。已知其可导致免疫功能低下患者发生肝炎和肝衰竭；在免疫功能正常的患者中，腺病毒是肝炎的罕见病因，且已知可导致暴发性肝衰竭。我们报告一例23个月大的免疫功能正常婴儿，该婴儿因腺病毒感染继发急性非胆汁淤积性肝炎、低白蛋白血症、全身性水肿和全血细胞减少。
