Wu Hongyan, Kanike Chiranjeevi, Atta Arnab, Zhang Xuehua
Department of Chemical and Materials Engineering, University of Alberta, Alberta T6G 1H9, Canada.
Department of Chemical Engineering, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India.
Biomicrofluidics. 2022 Oct 31;16(5):051502. doi: 10.1063/5.0121912. eCollection 2022 Sep.
Liquid-liquid extraction based on surface nanodroplets, namely nanoextraction, can continuously extract and enrich target analytes from the flow of a sample solution. This sample preconcentration technique is easy to operate in a continuous flow system with a low consumption of organic solvent and a high enrichment factor. In this review, the evolution from single drop microextraction to advanced nanoextraction will be briefly introduced. Moreover, the formation principle and key features of surface nanodroplets will be summarized. Further, the major findings of nanoextraction combined with in-droplet chemistry toward sensitive and quantitative detection will be discussed. Finally, we will give our perspectives for the future trend of nanoextraction.
基于表面纳米液滴的液-液萃取,即纳米萃取,能够从样品溶液流中持续萃取并富集目标分析物。这种样品预浓缩技术易于在连续流动系统中操作,有机溶剂消耗低且富集因子高。在本综述中,将简要介绍从单滴微萃取到先进纳米萃取的发展历程。此外,还将总结表面纳米液滴的形成原理和关键特性。进一步地,将讨论纳米萃取与液滴内化学相结合用于灵敏定量检测的主要研究成果。最后,我们将对纳米萃取的未来发展趋势发表看法。