Ando Reo, Taniguchi Shuichi, Arita Shuji, Aman Murasaki, Marutsuka Kousuke, Shimamoto Tomihiro
Department of Obstetrics and Gynecology, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Department of Chemotherapy, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Case Rep Obstet Gynecol. 2022 Oct 25;2022:7879220. doi: 10.1155/2022/7879220. eCollection 2022.
We report a case of an extragastrointestinal stromal tumor diagnosed as a vaginal mass during pregnancy. The mass was detected during routine examination at 24 weeks of gestation. At 26 weeks, the patient underwent transvaginal ultrasonography and magnetic resonance imaging, which revealed a blood flow-rich mass of approximately 50 × 30 mm in the rectovaginal septum. At 29 weeks of gestation, we resected the mass vaginally and the pathological diagnosis was a gastrointestinal stromal tumor. Chemotherapy was withheld until after full-term birth because the proliferation index of the tumor cells was low. The patient delivered a healthy infant. Imatinib was commenced at 1 month postpartum, with no recurrence or metastasis after 2.5 years. An extragastrointestinal stromal tumor as a vaginal mass in pregnancy has not been reported; however, our case suggests that the tumor should be considered a differential diagnosis of a vaginal mass in pregnancy.
我们报告一例在孕期被诊断为阴道肿物的胃肠道外间质瘤病例。该肿物在妊娠24周的常规检查中被发现。孕26周时,患者接受了经阴道超声检查和磁共振成像,结果显示在直肠阴道隔有一个血流丰富、大小约为50×30毫米的肿物。孕29周时,我们经阴道切除了该肿物,病理诊断为胃肠道间质瘤。由于肿瘤细胞的增殖指数较低,化疗推迟至足月分娩后进行。患者分娩出一名健康婴儿。产后1个月开始使用伊马替尼治疗,2.5年后无复发或转移。孕期以阴道肿物形式出现的胃肠道外间质瘤此前未见报道;然而,我们的病例提示,该肿瘤应被视为孕期阴道肿物的鉴别诊断之一。