一种用于关联tRNA序列与氨基酸特异性的统计方法。
A statistical method for correlating tRNA sequence with amino acid specificity.
作者信息
Atilgan T, Nicholas H B, McClain W H
出版信息
Nucleic Acids Res. 1986 Jan 10;14(1):375-80. doi: 10.1093/nar/14.1.375.
Abstract
A statistical method for finding the nucleotide positions in tRNA sequences that correlate with amino acid specificity has been developed. The procedure involves finding the subset of nucleotide positions and groups of positions where the marginal density of one amino acid tRNA class does not overlap that of any other amino acid class. The procedure is an application of a statistical method known as the Expectation Maximization algorithm.
摘要
一种用于确定与氨基酸特异性相关的tRNA序列中核苷酸位置的统计方法已经开发出来。该过程包括找到核苷酸位置的子集和位置组，其中一种氨基酸tRNA类别的边际密度与任何其他氨基酸类别的边际密度不重叠。该过程是一种称为期望最大化算法的统计方法的应用。
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