Department of Organic Materials Engineering, Chungnam National University, Daejeon 34134, South Korea.
CJ Cheiljedang Corp., Suwon-si, Gyeonggi-do 16495, South Korea.
Int J Biol Macromol. 2023 Jan 1;224:1487-1495. doi: 10.1016/j.ijbiomac.2022.10.237. Epub 2022 Oct 28.
In the past, plastic microbeads (MBs) were added to personal healthcare products to improve the cleaning and exfoliating effects, but these have been withdrawn owing to their non-degradable nature and contribution to the pollution of marine environment, especially that caused by the adsorption of persistent organic pollutants (POPs) on MBs. Therefore, natural biodegradable alternatives are being developed, but these often do not exhibit sufficient performance to replace non-degradable MBs. In this study, poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P3HB-4HB), a biodegradable aliphatic polyester, was used to prepare MBs via melt-electrospraying. We carried out the rheological characterization of P3HB-4HB with respect to melting temperature, and the melt-electrospray process was optimized to prepare MBs having sizes similar to those of commercially available MBs. Furthermore, the adsorption properties of the P3HB-4HB MBs for POPs were investigated. Unlike commercial MBs, the P3HB-4HB MBs adsorbed significantly fewer contaminants owing to their smooth and regular surfaces. Finally, a cleansing product containing P3HB-4HB MBs was prepared to evaluate their cleaning ability, and we found that the MB-based product could remove dirt and contaminants that were not easily removed by water alone. Thus, the biodegradable P3HB-4HB MBs have great potential for use as sustainable additives for cosmetic products for skin exfoliation.
过去，塑料微珠（MBs）被添加到个人保健产品中，以提高清洁和去角质效果，但由于其不可降解性以及对海洋环境污染的贡献，特别是对持久性有机污染物（POPs）在 MBs 上的吸附，这些 MBs 已被撤出。因此，正在开发天然可生物降解的替代品，但这些替代品通常不能表现出足够的性能来替代不可降解的 MBs。在本研究中，使用可生物降解的脂肪族聚酯聚（3-羟基丁酸酯-共-4-羟基丁酸酯）（P3HB-4HB）通过熔融静电纺丝制备 MBs。我们对 P3HB-4HB 的熔融温度进行了流变特性研究，并对熔融静电纺丝工艺进行了优化，以制备尺寸与市售 MBs 相似的 MBs。此外，还研究了 P3HB-4HB MBs 对 POPs 的吸附性能。与商业 MBs 不同，由于 P3HB-4HB MBs 的表面光滑且规则，因此它们吸附的污染物要少得多。最后，制备了含有 P3HB-4HB MBs 的清洁产品，以评估其清洁能力，我们发现基于 MBs 的产品可以去除仅用水不易去除的污垢和污染物。因此，可生物降解的 P3HB-4HB MBs 具有作为可持续性的化妆品产品的皮肤去角质添加剂的巨大潜力。
