Biorefineries for Biofuels & Bioproducts Laboratory (BBBL), Center for Trandisciplinary Research, Department of Pharmacology, SDC, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 600077, India.
Department of Botany, St. Mary's College (Autonomous), Thoothukudi, Tamil Nadu, India.
Bioresour Technol. 2023 Jan;367:128215. doi: 10.1016/j.biortech.2022.128215. Epub 2022 Nov 1.
Carotenoids are naturally occurring pigments that are widely distributed in algae, fungi, bacteria, and plants. Carotenoids play a significant role in the food, feed, cosmetic, nutraceutical, and pharmaceutical industries. These pigments are effectively considered as a health-promoting compounds, which are widely used in our daily diet to reduce the risk of chronic diseases such as cardiovascular diseases, cancer, acute lung injury, cataracts, neural disorders, etc. In this context, this review paper demonstrates the synthesis of carotenoids and their potential application in the food and pharmaceutical industries. However, the demand for carotenoid production is increasing overtime, and the extraction and production are expensive and technically challenging. The recent developments in carotenoid biosynthesis, and key challenges, bottlenecks, and future perspectives were also discussed to enhance the circular bioeconomy.
类胡萝卜素是广泛存在于藻类、真菌、细菌和植物中的天然色素。类胡萝卜素在食品、饲料、化妆品、营养保健品和制药行业中发挥着重要作用。这些色素被有效地视为具有促进健康作用的化合物，广泛应用于我们的日常饮食中，以降低心血管疾病、癌症、急性肺损伤、白内障、神经紊乱等慢性疾病的风险。在这种情况下，本文综述了类胡萝卜素的合成及其在食品和制药工业中的潜在应用。然而，类胡萝卜素的生产需求不断增加，提取和生产既昂贵又具有技术挑战性。本文还讨论了类胡萝卜素生物合成的最新进展、关键挑战、瓶颈以及未来展望，以增强循环生物经济。
