Long-Term Care Department, Hospital of Paul Doumer, Assistance Publique des Hôpitaux de Paris (AP-HP), Labruyère, France.
Pharmacy Department, Hospital of Paul Doumer, Assistance Publique des Hôpitaux de Paris (AP-HP), Labruyère, France.
Ir J Med Sci. 2023 Aug;192(4):1661-1664. doi: 10.1007/s11845-022-03207-3. Epub 2022 Nov 4.
We evaluated the use of the PPI treatment by physicians in older adults hospitalized in a long-term care unit.
We included 40 patients aged 65 years or older with a lansoprazole prescription hospitalized in long-term care unit from January 2018 to January 2022. Patient characteristics, gastroduodenal history, dose of lansoprazole, indication, days of prescription, and number of medications were collected from electronic patient records.
The mean age of patients was 84.2 ± 9.3. Patients were taking between 5 and 24 (mean = 12.7, SD = 4.4) medications overall with 15 patients taking low dose of aspirin (75 mg daily) and 8 patients taking an antiplatelet. Most patients (82.5%) received once-daily lansoprazole treatment, 55% of whom took a dose of 15 mg. Five patients were treated with the maximum dose of lansoprazole 30 mg twice daily. Only seven patients had an appropriate indication. The minimum of treatment time was 3 days and the maximum was 1198 days; moreover, 24 patients (60%) were still in treatment.
Few PPI prescriptions had an indication in the patient's electronic record. Prescriptions were ongoing with no date of discontinuation or re-evaluation.
我们评估了在长期护理病房住院的老年患者中，医生使用质子泵抑制剂（PPI）治疗的情况。
我们纳入了 2018 年 1 月至 2022 年 1 月期间在长期护理病房住院且开具了兰索拉唑处方的 40 名 65 岁及以上的患者。从电子病历中收集了患者特征、胃十二指肠疾病史、兰索拉唑剂量、适应证、处方天数和用药数量等信息。
患者的平均年龄为 84.2±9.3 岁。他们总共服用了 5 至 24 种（平均 12.7，标准差 4.4）药物，其中 15 名患者服用低剂量阿司匹林（每日 75mg），8 名患者服用抗血小板药物。大多数患者（82.5%）接受了每日一次的兰索拉唑治疗，其中 55%的患者服用 15mg 剂量。有 5 名患者接受了兰索拉唑最大剂量（30mg，每日 2 次）治疗。仅有 7 名患者的适应证恰当。治疗时间最短为 3 天，最长为 1198 天；此外，24 名患者（60%）仍在接受治疗。
患者的电子病历中仅有少数 PPI 处方有适应证。处方仍在继续，没有停药或重新评估的日期。
