Recent update of the various sources originating ghost peaks in gas chromatography: A review.

Gas chromatography (GC) is a versatile tool for separating various volatile, semi-volatile, and thermally stable compounds. However, the ghost peaks in the GC are now a major concern for chromatographic analysts. Ghost peaks may interfere with the analyte, leading to inaccurate results, so identifying the sources generating these peaks is essential for the validated analysis of the compounds of interest. This review compiles various sources responsible for generating ghost peaks in the GC and their possible troubleshooting methods for the smooth and consistent running of the ghost peak-free gas chromatography system, which will be very helpful for rapid and validated analysis.