Schwartz H J
Hosp Community Psychiatry. 1979 Jul;30(7):465-7. doi: 10.1176/ps.30.7.465.
A psychiatric patient's long-term use of antipsychotic medication often results in the irreversible movement disorder, tardive dyskinesia. The author uses a composite case history as a basis for discussing the symptoms, diagnosis, epidemiology, and treatment of tardive dyskinesia. A number of drugs have been used to treat the disorder, but so far none have been effective. While tardive dyskinesia cannot be cured at this time, the author believes that it can be prevented by treating psychoses with the lowest possible dose of the least toxic drug for the shortest length of time.
精神病患者长期使用抗精神病药物常常会导致不可逆的运动障碍——迟发性运动障碍。作者以一个综合病例史为基础,讨论迟发性运动障碍的症状、诊断、流行病学及治疗。已有多种药物用于治疗该疾病,但目前尚无一种有效。虽然迟发性运动障碍目前无法治愈,但作者认为,通过使用毒性最小的药物、以尽可能低的剂量、在最短的时间内治疗精神病,可以预防该病。