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利用 Sphinx Compact 进行均匀扫描质子治疗质量保证的可行性研究。

Feasibility study of utilizing Sphinx Compact for quality assurance in uniform scanning proton therapy.

机构信息

Department of Medical Physics, The Oklahoma Proton Center, Oklahoma City, OK, USA; Department of Radiation Oncology, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Boca Raton, FL, USA; Department of Radiation Oncology, Florida International University, Miami, FL, USA.

Department of Medical Physics, The Oklahoma Proton Center, Oklahoma City, OK, USA.

出版信息

Phys Med. 2023 Sep;113:102468. doi: 10.1016/j.ejmp.2022.10.001. Epub 2022 Nov 3.

Abstract

PURPOSE

To investigate the feasibility of utilizing the Sphinx Compact detector for quality assurance in a uniform scanning proton therapy system.

METHOD

The Sphinx Compact detector was used to measure various dosimetric parameters of uniform scanning proton beam at the Oklahoma Proton Center: distal range, distal-fall-off, collinearity, field symmetry, flatness, and field size for four different beams. A specially designed brass aperture was used to perform the required measurements. The Sphinx Compact measurement results were validated against the measurement results from the well-established detectors in proton therapy: IBA Zebra, IBA MatriXX-PT, EBT3 films, and Logos XRV-124. The data collected using the Sphinx Compact was analyzed in myQA software.

RESULTS

Based on the data analysis performed, the Sphinx Compact measurements were within acceptable accuracy to the results from the detectors mentioned in the Method section. Specifically, the lateral penumbra was within ±0.4 mm, collinearity was within ± 0.5 mm, flatness was within ±0.6 %, symmetry within ±1.6 %, distal range was within ±0.5 mm, distal-fall-off was <0.9 mm, and field size was within ±1 mm. The reproducibility of the Sphinx Compact was tested for range and collinearity, and the results were within ±0.1 mm.

CONCLUSION

The sphinx Compact detector could potentially replace multiple detectors utilized for monthly QA in uniform scanning proton therapy. In a multi-room center, performing the QA with one detector compared to using multiple detectors dramatically reduces total QA time and the complexity of the QA process.

摘要

目的

研究利用 Sphinx Compact 探测器在统一扫描质子治疗系统中进行质量保证的可行性。

方法

Sphinx Compact 探测器用于测量俄克拉荷马质子中心均匀扫描质子束的各种剂量学参数:远距、远距下降、共线性、场对称性、平坦度和四个不同束的射野大小。使用特殊设计的黄铜孔径进行所需的测量。Sphinx Compact 的测量结果与质子治疗中成熟的探测器的测量结果进行了验证:IBA Zebra、IBA MatriXX-PT、EBT3 薄膜和 Logos XRV-124。使用 Sphinx Compact 收集的数据在 myQA 软件中进行了分析。

结果

根据所进行的数据分析,Sphinx Compact 的测量结果与方法部分中提到的探测器的结果在可接受的精度范围内。具体而言,侧向半影在 ±0.4mm 以内,共线性在 ±0.5mm 以内,平坦度在 ±0.6%以内,对称性在 ±1.6%以内,远距在 ±0.5mm 以内,远距下降在 <0.9mm 以内,射野大小在 ±1mm 以内。对 Sphinx Compact 的重复性进行了测试,结果在 ±0.1mm 以内。

结论

Sphinx Compact 探测器有可能替代用于均匀扫描质子治疗的每月 QA 的多个探测器。在多间治疗室的中心,使用一个探测器进行 QA 与使用多个探测器相比,可大大减少总 QA 时间和 QA 过程的复杂性。

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