Ackerman N R, Beebe J R, Schidlovsky G
Cytobios. 1977;20(77):7-20.
Cells lavaged from guinea pig lungs selectively release the lysosomal enzymes beta-glucuronidase and lysozyme during the process of phagocytosis. The total enzymatic activity of beta-glucuronidase was elevated in zymosan-exposed compared with non-exposed cells. The divalent cation carrying ionophore A23187 did not stimulate lysosomal enzyme release. Transmission and scanning electron micrographs demonstrate particle uptake and are consistent with enzyme release.
从豚鼠肺中冲洗出的细胞在吞噬过程中选择性地释放溶酶体酶β-葡萄糖醛酸酶和溶菌酶。与未接触酵母聚糖的细胞相比,接触酵母聚糖的细胞中β-葡萄糖醛酸酶的总酶活性有所升高。携带二价阳离子的离子载体A23187不会刺激溶酶体酶的释放。透射电子显微镜和扫描电子显微镜图像显示了颗粒摄取情况,并且与酶的释放情况相符。