Cavalcante-Neto Joaquim Francisco, Dos Reis Gabriel Costa, Esmeraldo Mateus Aragão, Dos Santos Bianca Ratts Freitas, Leal Paulo Roberto Lacerda, da Ponte Keven Ferreira, Cristino-Filho Gerardo, Ribeiro Espártaco Moraes Lima
Department of Neurology, Federal University of Ceará, Sobral, Brazil.
Department of Neurology, Santa Casa de Misericórdia de Sobral, Sobral, Brazil.
Neuroophthalmology. 2022 Mar 21;46(5):335-338. doi: 10.1080/01658107.2022.2043390. eCollection 2022.
Eight-and-a-half syndrome (EHS) is a neuro-ophthalmological condition characterised by horizontal gaze palsy, internuclear ophthalmoplegia, and ipsilateral facial palsy. Albeit rare, EHS is a well reported condition in the literature, with several reports presenting multiple aetiologies. Infarcts are the cause in more than half the cases. Human immunodeficiency virus (HIV)-related cases are rare, and are probably underreported in low- and middle-income countries. In this report, we describe EHS secondary to neurotoxoplasmosis in a 40-year-old HIV-positive Brazilian man. EHS secondary to neurotoxoplasmosis is a challenging diagnosis, with important differential diagnoses, notably for HIV patients.
八又二分之一综合征（EHS）是一种神经眼科疾病，其特征为水平凝视麻痹、核间性眼肌麻痹和同侧面神经麻痹。尽管EHS很罕见，但在文献中已有充分报道，有几篇报告提出了多种病因。超过半数的病例病因是梗死。与人类免疫缺陷病毒（HIV）相关的病例很少见，在低收入和中等收入国家可能报告不足。在本报告中，我们描述了一名40岁HIV阳性巴西男子继发于神经型弓形虫病的EHS。继发于神经型弓形虫病的EHS诊断具有挑战性，存在重要的鉴别诊断，尤其是对于HIV患者。
