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手部背侧坏疽性脓皮病:一例报告

Pyoderma Gangrenosum Affecting the Dorsal Hand: A Case Report.

作者信息

Haase Lucas R, Nelson Grant B, Klyce Walter B, Cavaliere Christi M, Bafus Blaine T

机构信息

Department of Orthopedic Surgery, Louis Stokes Cleveland VA Medical Center,Cleveland, Ohio.

University Hospitals Cleveland Medical Center, Department of Orthopedic Surgery, Cleveland Ohio.

出版信息

Plast Reconstr Surg Glob Open. 2022 Nov 1;10(11):e4592. doi: 10.1097/GOX.0000000000004592. eCollection 2022 Nov.

Abstract

Pyoderma gangrenosum is an uncommon neutrophilic dermatosis characterized by an ulcerative lesion with a violaceous border. Most frequently, these lesions present in the lower extremity and are associated with underlying immune-mediated comorbidities. Infrequently, these lesions may present in the upper extremity, which presents difficult challenges for upper extremity surgeons as the lesions are frequently misdiagnosed as an infectious process. This often leads to inappropriate surgical debridement and antibiotic administration. Local trauma to the lesion can lead to a process of pathergy and worsening of the lesion. Here, we report on a case of cutaneous pyoderma gangrenosum affecting the dorsal hand, originally misidentified as an atypical infection with subsequent unsuccessful surgical debridement. After involvement of a multidisciplinary team, appropriate diagnosis was made, and treatment with local immunosuppressive agents achieved resolution of the lesion.

摘要

坏疽性脓皮病是一种罕见的嗜中性皮病,其特征为具有紫罗兰色边缘的溃疡性病变。这些病变最常出现在下肢,并与潜在的免疫介导合并症相关。病变很少出现在上肢,这给上肢外科医生带来了难题,因为这些病变常被误诊为感染性疾病。这往往导致不适当的手术清创和抗生素使用。病变部位的局部创伤可导致同形反应,使病变恶化。在此,我们报告一例累及手背的皮肤坏疽性脓皮病病例,最初被误诊为非典型感染,随后手术清创未成功。在多学科团队参与后,做出了正确诊断,局部使用免疫抑制剂治疗使病变得以消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b59/9624498/79002513180e/gox-10-e4592-g001.jpg

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