Kono Yumiko, Utsunomiya Keita, Ohe Chisato, Takizawa Nae, Tanigawa Noboru
Department of Radiology, Kansai Medical University, Osaka, JPN.
Department of Pathology and Laboratory Medicine, Kansai Medical University, Osaka, JPN.
Cureus. 2022 Oct 2;14(10):e29827. doi: 10.7759/cureus.29827. eCollection 2022 Oct.
Imaging is useful in identifying the primary site of an unknown primary cancer, and F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) is an excellent imaging modality for identifying the primary lesion. However, a potential limitation is that F-FDG is physiologically excreted from the kidneys, thus masking renal lesions. In this report, we describe two cases of cancer of unknown origin that were detected as originating from renal cancer on F-FDG PET/CT. Both cases showed abnormal nodular accumulation of F-FDG in the kidney, which can be distinguished from the physiological excretion of F-FDG in the urinary tract. It is clinically crucial to be able to confirm the possibility of renal cancer, and careful observation of the urinary tract with F-FDG PET/CT can be useful.
影像学检查有助于确定原发性不明癌症的原发部位，氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-FDG PET/CT）是识别原发性病变的一种优秀影像学检查方法。然而，一个潜在的局限性是F-FDG会经肾脏生理性排泄，从而掩盖肾脏病变。在本报告中，我们描述了两例原发性不明癌症病例，它们在F-FDG PET/CT检查中被检测出起源于肾癌。两例病例均显示肾脏出现F-FDG异常结节状聚集，这可与F-FDG在尿路中的生理性排泄相区分。能够确认肾癌的可能性在临床上至关重要，而通过F-FDG PET/CT仔细观察尿路可能会有所帮助。
