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全喉切除术后吻合口密封处漏液后持续性下咽假单胞菌感染

Persistent Neopharynx Pseudomonas Infection After a Sealed Anastomotic Leak Post Total Laryngectomy.

作者信息

Mat Baki Marina, Mohd Ridzam Mohd Syafeeq, Abdul Rahim Norazila

机构信息

Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.

Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universiti Teknologi MARA (UiTM) Sungai Buloh Campus, Selangor, MYS.

出版信息

Cureus. 2022 Oct 1;14(10):e29802. doi: 10.7759/cureus.29802. eCollection 2022 Oct.

DOI:10.7759/cureus.29802
PMID:36337830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9622029/
Abstract

Total laryngectomy (TL) is the treatment of choice for advanced glottic cancer. Post-operative complications can be debilitating for patients, family members and healthcare workers. Complications following TL have been reported in many studies, with pharyngocutaneous fistula and wound infection being the most common. Identifying the risk factors that may give rise to these complications is vital to minimise post-operative morbidity. We present the case of a 62-year-old male who underwent salvage TL following radiation therapy for recurrent glottic carcinoma. The patient developed diffuse submental swelling upon the commencement of oral feeding. A flexible nasopharyngolaryngoscopy revealed a sloughy area at the neopharynx, with the finding of a sealed anastomotic leak on a repeat barium swallow study. We report persistent infection following salvage TL, after a sealed anastomotic leak.

摘要

全喉切除术(TL)是晚期声门癌的首选治疗方法。术后并发症可能会使患者、家属和医护人员感到虚弱。许多研究都报道了全喉切除术后的并发症,其中咽皮肤瘘和伤口感染最为常见。识别可能导致这些并发症的危险因素对于将术后发病率降至最低至关重要。我们报告了一例62岁男性患者,该患者因复发性声门癌接受放疗后进行了挽救性全喉切除术。患者开始经口进食后出现颏下弥漫性肿胀。纤维鼻咽喉镜检查显示鼻咽部有一个溃疡区域,重复钡餐吞咽研究发现吻合口密封处有渗漏。我们报告了挽救性全喉切除术后,在吻合口密封处渗漏后出现持续感染的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b463/9622029/8be5a372601b/cureus-0014-00000029802-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b463/9622029/d77b091c54aa/cureus-0014-00000029802-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b463/9622029/ef555c9b73f1/cureus-0014-00000029802-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b463/9622029/92e169bba949/cureus-0014-00000029802-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b463/9622029/8be5a372601b/cureus-0014-00000029802-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b463/9622029/d77b091c54aa/cureus-0014-00000029802-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b463/9622029/ef555c9b73f1/cureus-0014-00000029802-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b463/9622029/92e169bba949/cureus-0014-00000029802-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b463/9622029/8be5a372601b/cureus-0014-00000029802-i04.jpg

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本文引用的文献

1
Intraoperative Dye Test in Total Laryngectomy: A Technique to Reduce the Incidence of Pharyngocutaneous Fistula.全喉切除术中的术中染料试验:一种降低咽皮肤瘘发生率的技术。
Niger J Surg. 2020 Jul-Dec;26(2):127-129. doi: 10.4103/njs.NJS_69_19. Epub 2020 Jul 27.
2
Functional Outcomes and Complications After Salvage Total Laryngectomy for Residual, Recurrent, and Second Primary Squamous Cell Carcinoma of the Larynx and Hypopharynx: A Multicenter Retrospective Cohort Study.喉和下咽残余、复发及第二原发鳞状细胞癌挽救性全喉切除术后的功能结局与并发症:一项多中心回顾性队列研究
Front Oncol. 2020 Sep 2;10:1390. doi: 10.3389/fonc.2020.01390. eCollection 2020.
3
Epidemiology of head and neck cancers: an update.
头颈部癌症的流行病学:最新研究进展。
Curr Opin Oncol. 2020 May;32(3):178-186. doi: 10.1097/CCO.0000000000000629.
4
Updates on larynx cancer epidemiology.喉癌流行病学的最新进展。
Chin J Cancer Res. 2020 Feb;32(1):18-25. doi: 10.21147/j.issn.1000-9604.2020.01.03.
5
Early oral hydration protects against pharyngocutaneous fistula after total laryngectomy or total pharyngolaryngectomy.早期口服补水可预防全喉切除术或全下咽喉切除术后咽皮肤瘘的发生。
Head Neck. 2020 Aug;42(8):1902-1906. doi: 10.1002/hed.26122. Epub 2020 Mar 3.
6
Contemporary management of advanced laryngeal cancer.晚期喉癌的现代治疗
Laryngoscope Investig Otolaryngol. 2017 Jul 29;2(5):307-309. doi: 10.1002/lio2.85. eCollection 2017 Oct.
7
Guidelines for the Surgical Management of Laryngeal Cancer: Korean Society of Thyroid-Head and Neck Surgery.喉癌手术治疗指南:韩国甲状腺头颈外科学会
Clin Exp Otorhinolaryngol. 2017 Mar;10(1):1-43. doi: 10.21053/ceo.2016.01389. Epub 2017 Jan 3.
8
Evidence-based practice: management of glottic cancer.循证实践:声门癌的管理
Otolaryngol Clin North Am. 2012 Oct;45(5):1143-61. doi: 10.1016/j.otc.2012.06.014. Epub 2012 Jul 31.
9
Post-operative wound infection in salvage laryngectomy: does antibiotic prophylaxis have an impact?挽救性喉切除术术后伤口感染:抗生素预防是否有影响?
Eur Arch Otorhinolaryngol. 2012 Nov;269(11):2415-22. doi: 10.1007/s00405-012-1932-8. Epub 2012 Jan 25.