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关于金属-金属相互作用问题的理论与实践思考

Theoretical and practical considerations on the problem of metal--metal interaction.

作者信息

Magos L, Webb M

出版信息

Environ Health Perspect. 1978 Aug;25:151-4. doi: 10.1289/ehp.7825151.

DOI:10.1289/ehp.7825151
PMID:363406
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1637192/
Abstract

The interaction between two metals, which can be either synergistic or antagonistic, implies that the behavior of one is changed by the presence of the other. Possible mechanisms of these interactions, which include chemical association, competition for carriers, metabolic changes, induction of binding proteins, membrane alterations are discussed.

摘要

两种金属之间的相互作用,可能是协同的,也可能是拮抗的,这意味着一种金属的行为会因另一种金属的存在而改变。本文讨论了这些相互作用的可能机制,包括化学缔合、载体竞争、代谢变化、结合蛋白的诱导、膜改变。

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本文引用的文献

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Binding of cadmium and mercury by metallothionein in the kidneys and liver of rats following repeated administration.大鼠反复给药后肾脏和肝脏中金属硫蛋白对镉和汞的结合作用。
Arch Toxicol. 1974;32(4):351-60. doi: 10.1007/BF00330118.
10
Diversion of mercury binding in rat tissues by selenium: a possible mechanism of protection.硒对大鼠组织中汞结合的转移作用:一种可能的保护机制。
Pharmacol Res Commun. 1974 Dec;6(6):571-9. doi: 10.1016/s0031-6989(74)80006-8.