Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI, USA.
Curr Opin Chem Biol. 2013 Apr;17(2):197-203. doi: 10.1016/j.cbpa.2012.12.011. Epub 2013 Jan 23.
Metal complexes are efficient catalysts for protein inactivation. Because of their special reactivity, metal-based molecules can achieve results that are difficult, if not impossible to obtain with more traditional, organic-based inhibitors. This article summarizes the chemistry of hydrolytic and oxidative catalysts for protein inactivation.
金属配合物是高效的蛋白质失活催化剂。由于其特殊的反应活性，基于金属的分子可以实现，如果不是不可能的话，用更传统的基于有机的抑制剂难以实现的结果。本文总结了水解和氧化催化剂在蛋白质失活方面的化学性质。
