Cai Hui, Cui Yong, Cravens Lauryn, Yang Gong, Yu Danxia, Gao Yu-Tang, Zheng Wei, Shu Xiao-Ou
Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, Nashville, TN 37203, USA.
Hubert Department of Global Health, Emory University, Rollins School of Public Health, 1518 Clifton Road NE, Room 738, Atlanta, GA 30322, USA.
Arch Gerontol Geriatr. 2023 Feb;105:104848. doi: 10.1016/j.archger.2022.104848. Epub 2022 Oct 26.
To examine the associations between lifestyle habits and functional impairments among older adults.
The study includes 20,545 women and 14,374 men aged 70 years or older at the time of the function assessment. Participants were from two prospective cohort studies: the Shanghai Women's Health Study (SWHS, enrollment from 1996 to 2000) and the Shanghai Men's Health Study (SMHS, enrollment from 2002 to 2006). Lifestyle information was collected at study enrollment and a healthy lifestyle score (HLS) was derived. Functional impairment information was collected at the follow-up survey conducted in 2012-2017. Logistic regression analyses were applied to estimate the associations of HLS with functional impairments.
The average age at lifestyle and functional impairment assessment was 62.3 (range: 49.9-70.9) and 77.7 (range: 70.0-89.4) for women and 67.5 (range: 55.1-74.9) and 77.4 (range: 70.0-88.6) for men. After a median follow-up of 14.4 years, we found that the HLS was inversely associated with overall severe functional impairment: odds ratio (95% confidence interval), 0.78(0.71-0.86) and individual severe functional impairment: 0.67(0.62-0.73) for independent walking, 0.85(0.77-0.94) for hearing/vision, 0.79(0.70-0.88) for memory, and 0.74(0.67-0.82) for decision-making impairment, comparing the highest with the lowest HLS categories. Such associations were similar among individuals with/without cardiometabolic diseases at baseline. The associations between each lifestyle factor and functional impairments differed.
A healthy lifestyle was associated with reduced odds of physical and mental impairment among older Chinese adults, emphasizing the importance of promoting and maintaining a healthy lifestyle to prevent or postpone age-related functional impairments.
研究老年人生活方式习惯与功能障碍之间的关联。
本研究纳入了20545名女性和14374名男性，在进行功能评估时年龄均在70岁及以上。参与者来自两项前瞻性队列研究：上海女性健康研究（SWHS，1996年至2000年招募）和上海男性健康研究（SMHS，2002年至2006年招募）。在研究入组时收集生活方式信息，并得出健康生活方式评分（HLS）。在2012年至2017年进行的随访调查中收集功能障碍信息。应用逻辑回归分析来估计HLS与功能障碍之间的关联。
女性在生活方式和功能障碍评估时的平均年龄分别为62.3岁（范围：49.9 - 70.9岁）和77.7岁（范围：70.0 - 89.4岁），男性分别为67.5岁（范围：55.1 - 74.9岁）和77.4岁（范围：70.0 - 88.6岁）。经过中位数为14.4年的随访，我们发现HLS与总体严重功能障碍呈负相关：比值比（95%置信区间）为0.78（0.71 - 0.86），与个体严重功能障碍也呈负相关：独立行走方面为0.67（0.62 - 0.73），听力/视力方面为0.85（0.77 - 0.94），记忆力方面为0.79（0.70 - 0.88），决策能力障碍方面为0.74（0.67 - 0.82），最高HLS类别与最低HLS类别相比。在基线时有/无心血管代谢疾病的个体中，这种关联相似。各生活方式因素与功能障碍之间的关联有所不同。
健康的生活方式与中国老年成年人身心功能障碍几率降低相关，强调了促进和保持健康生活方式以预防或推迟与年龄相关的功能障碍的重要性。
