Cardiologist at United Medical Doctors, La Jolla, CA, USA.
Department of Cardiology, Scripps Clinic, La Jolla, CA, USA.
Curr Atheroscler Rep. 2022 Dec;24(12):981-993. doi: 10.1007/s11883-022-01072-0. Epub 2022 Nov 8.
Focused review of select studies presented at the 2022 European Society of Cardiology Congress.
Included studies assessed the effects of aspirin and omega-3 fatty acid supplements on heart failure (ASCEND study); the impact of icosapent ethyl on ST-elevation MI incidence (REDUCE-IT); air temperature's effect on cardiovascular mortality (EXHAUSTION project); LVEF outcomes after troponin-guided neurohormonal blockade for the prevention of anthracycline toxicity; efficacy of routine stress testing after high-risk PCI (POST-PCI trial); influenza vaccine among patients with acute coronary syndromes (VIP-ACS trial); empagliflozin in patients with acute myocardial infarction (EMMY); effects of comprehensive imaging-based cardiovascular screening on death and cardiovascular events (DANCANVAS); safety of long-term evolocumab in patients with established atherosclerotic cardiovascular disease (FOURIER-OLE); and use of a cardiovascular polypill as a global strategy to improve secondary prevention (SECURE). Research presented at the 2022 ESC Congress highlighted many novel applications of preventative and treatment strategies in cardiology, including the effects of environmental risk factors on the incidence of cardiovascular disease.
重点回顾 2022 年欧洲心脏病学会大会上呈现的部分精选研究。
包括评估阿司匹林和欧米伽-3 脂肪酸补充剂对心力衰竭影响的研究(ASCEND 研究);icosapent ethyl 对 ST 段抬高型心肌梗死发生率的影响(REDUCE-IT 研究);气温对心血管死亡率的影响(EXHAUSTION 项目);肌钙蛋白指导的神经激素阻断预防蒽环类药物毒性的左心室射血分数结局;高危经皮冠状动脉介入治疗(POST-PCI 试验)后常规应激试验的疗效;急性冠状动脉综合征患者的流感疫苗(VIP-ACS 试验);急性心肌梗死患者的恩格列净(EMMY 研究);基于综合影像学的心血管筛查对死亡和心血管事件的影响(DANCANVAS);在已确诊的动脉粥样硬化性心血管疾病患者中使用依洛尤单抗的安全性(FOURIER-OLE);以及使用心血管复方片作为改善二级预防的全球策略(SECURE)。2022 年 ESC 大会上呈现的研究强调了心血管预防和治疗策略的许多新应用,包括环境危险因素对心血管疾病发生率的影响。