Department of Cardiology, Scripps Clinic, La Jolla, CA, USA.
Department of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Curr Atheroscler Rep. 2022 Aug;24(8):671-680. doi: 10.1007/s11883-022-01042-6. Epub 2022 May 28.
Focused review highlighting select studies presented at the 2022 American College of Cardiology (ACC) Scientific Sessions.
Included studies assessed the impact of a low-sodium diet on heart failure outcomes (SODIUM-HF); outcomes of pregnant patients with chronic hypertension treated with antihypertensive therapies (CHAP); cardiovascular outcomes in patients with type 2 diabetes and renal impairment treated with sotagliflozin (SCORED); a safety and efficacy study investigating SLN360, a short interfering RNA targeting lipoprotein(a) (APOLLO); a supermarket and web-based intervention targeting nutrition for cardiovascular risk reduction (SuperWIN); a superiority trial comparing myocardial injury following very mild perioperative hypothermia versus aggressive warming after non-cardiac surgery (PROTECT); and 3-year efficacy outcomes of renal denervation on blood pressure reduction from the SPYRAL HTN-ON MED pilot study. Research presented at the 2022 ACC Scientific Sessions underscores the new potential and meaningful impact of cardiovascular disease prevention and management interventions.
目的综述：重点回顾了在 2022 年美国心脏病学会（ACC）科学会议上展示的部分精选研究。
最新发现：这些研究评估了低盐饮食对心力衰竭结局的影响（SODIUM-HF）；接受降压治疗的慢性高血压孕妇的结局（CHAP）；在伴有肾功能损害的 2 型糖尿病患者中使用索格列净的心血管结局（SCORED）；一项旨在评估靶向脂蛋白(a)的短干扰 RNA SLN360 的安全性和疗效的研究（APOLLO）；旨在通过超市和网络干预降低心血管风险的营养研究（SuperWIN）；一项比较非心脏手术后轻度围手术期低温与积极复温对心肌损伤的优越性试验（PROTECT）；以及 SPYRAL HTN-ON MED 先导研究中肾去神经术对血压降低的 3 年疗效。2022 年 ACC 科学会议上展示的研究强调了心血管疾病预防和管理干预的新潜力和重要影响。
