吲哚洛尔：一种用于治疗高血压的强效β-肾上腺素能阻滞剂。

Pindolol: a potent beta-adrenergic blocking agent in the treatment of hypertension.

作者信息

Jaroonvesma N, Charoenlarp K

出版信息

J Int Med Res. 1978;6(6):435-40. doi: 10.1177/030006057800600603.

Abstract

Two groups of twenty-five hypertensive patients each were treated with a beta-adrenergic blocking agent (pindolol), either alone or in combination with classical anthihypertensives. In the group under monotherapy a significant lowering of the blood pressure was observed. The effect was, however, not so consistent as in the group under combined therapy. The trial shows the efficacy and safety of pindolol in the treatment of hypertension mainly if applied in combination with a diuretic.

摘要

两组各25名高血压患者接受了β-肾上腺素能阻滞剂（吲哚洛尔）治疗，治疗方式分别为单独使用或与传统抗高血压药物联合使用。在单一疗法组中观察到血压显著降低。然而，这种效果不如联合治疗组那样稳定。该试验表明，吲哚洛尔在治疗高血压方面具有疗效和安全性，主要是在与利尿剂联合使用时。