Zhang Cheng, Stampfl-Mattersberger Margarete, Ruckser Reinhard, Sebesta Christian
2. Medizinische Abteilung, Klinik Donaustadt, Wiener Gesundheitsverbund, Wien, Österreich, Langobardenstraße 122, 1220.
Wien Med Wochenschr. 2023 Jun;173(9-10):216-220. doi: 10.1007/s10354-022-00975-6. Epub 2022 Nov 8.
Being one of the most common tumor entities worldwide, the colorectal carcinoma accounts for approximately 10% of all tumor-related deaths. With screening programs such as preventive colonoscopy, a decreasing incidence and mortality rate can be seen in the last decades. Many risk factors, which favor or prevent the development of colorectal carcinoma, can be traced back to lifestyle choices. Many patients with localized disease can be cured through tumor resection and adjuvant chemotherapy, in systemic disease, targeted therapy and immunotherapy have improved survival in the last years. This article aims to provide an overview on the basic epidemiologic, diagnostic and therapeutic principles of colorectal carcinoma, as well as a short excerpt of the newest therapeutic developments.
作为全球最常见的肿瘤类型之一，结直肠癌约占所有肿瘤相关死亡人数的10%。通过诸如预防性结肠镜检查等筛查项目，在过去几十年中可观察到发病率和死亡率呈下降趋势。许多促进或预防结直肠癌发生的危险因素可追溯到生活方式的选择。许多局限性疾病患者可通过肿瘤切除和辅助化疗治愈，对于全身性疾病，靶向治疗和免疫治疗在过去几年中提高了生存率。本文旨在概述结直肠癌的基本流行病学、诊断和治疗原则，以及最新治疗进展的简短摘录。
