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通过生物力学模拟解决造口旁疝。

Addressing parastomal herniation through biomechanical simulation.

机构信息

Surgical Registrar, Salisbury District Hospital, Salisbury NHS Foundation Trust, Southampton, UK.

出版信息

Hernia. 2023 Jun;27(3):565-573. doi: 10.1007/s10029-022-02704-9. Epub 2022 Nov 8.

DOI:10.1007/s10029-022-02704-9
PMID:36348226
Abstract

PURPOSE

Parastomal hernia remains a significant source of post-operative morbidity. Existing surgical solutions have shown limited success while not addressing the biomechanics underpinning parastomal herniation. The primary objective was to examine the influence of stoma aperture shape on abdominal wall stress and tissue destruction. The secondary objective compared mesh designs with respect to abdominal wall stress.

METHODS

Finite element analysis of an abdominal wall model was used to simulate various stoma and mesh designs. The outcome measures were abdominal wall (mmHg) pressure required to initiate tissue tearing, stress distribution and median and peak abdominal wall stress (N/m).

RESULTS

The simulation demonstrated that the cruciate stoma incision developed high stress concentration at the apices of the slit incisions. The circular stoma incision distributed stress uniformly. The circular stoma design was more resistant to tissue tearing. The Keyhole mesh design demonstrated the lowest median and peak stress at 17.32 and 28.01 N/m. This was a statically significant reduction in stress compared to the Sugar Baker and no mesh designs (p < 0.001).There were no significant differences between the Keyhole mesh design and loose mesh designs as long as the loose mesh design aperture did not exceed 1.5 times the stoma aperture diameter (p = 0.223).

CONCLUSIONS

This study has demonstrated that the shape of the fascia incision and mesh design have a significant impact on parastomal hernia formation. Novel designs can be used to optimise the stoma. The circular stoma and loose mesh designs are promising avenues for future research.

摘要

目的

造口旁疝仍然是术后发病率的一个重要来源。现有的手术解决方案显示出有限的成功,同时也没有解决造口旁疝的生物力学问题。主要目的是研究造口孔径形状对腹壁应力和组织破坏的影响。次要目的是比较网片设计对腹壁应力的影响。

方法

使用有限元分析对腹壁模型进行模拟,以模拟各种造口和网片设计。测量指标为启动组织撕裂所需的腹壁(mmHg)压力、应力分布以及腹壁的中位数和峰值压力(N/m)。

结果

模拟结果表明,十字形造口切口在切口的顶点处产生了高的应力集中。圆形造口切口均匀地分布了应力。圆形造口设计更能抵抗组织撕裂。钥匙孔网片设计的中位数和峰值压力分别为 17.32 和 28.01 N/m,与 Sugar Baker 和无网片设计相比,压力明显降低(p<0.001)。只要松散网片设计的孔径不超过造口孔径直径的 1.5 倍,钥匙孔网片设计与松散网片设计之间没有显著差异(p=0.223)。

结论

本研究表明,筋膜切口的形状和网片设计对造口旁疝的形成有显著影响。新型设计可用于优化造口。圆形造口和松散网片设计是未来研究的有前途的途径。

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