Children's Health and Environment Program, Child Health Research Centre, The University of Queensland, Australia.
Superfund Research Program, National Institute of Environmental Health Sciences, USA.
Ann Glob Health. 2022 Oct 21;88(1):91. doi: 10.5334/aogh.3670. eCollection 2022.
This article summarises a session from the recent Pacific Basin Consortium for Environment and Health Focus meeting on Environmental Impacts on Infectious Disease.
To provide an overview of the literature underpinning the presentations from this session.
References used in developing the presentations were obtained from the presenters. Additional references were obtained from PubMed using key words from the presentations.
The Hokkaido longitudinal children's study has found that exposure to chemicals in early life, such as persistent organic pollutants and per/polyfluorinated compounds, is associated with a range of immunological outcomes such as decreased cord blood IgE, otitis media, wheeze, increased risk of infections and higher risk of food allergy.Epidemiological evidence links exposure to poor air quality to increased severity and mortality of Covid-19 in many parts of the world. Most studies suggest that long-term exposure has a more marked effect than acute exposure.Components of air pollution, such as a newly described combustion product known as environmentally persistent free radicals, induce oxidative stress in exposed individuals. Individuals with genetic variations predisposing them to oxidative stress are at increased risk of adverse health effects from poor air quality.
本文总结了最近太平洋盆地环境与健康联盟重点会议上关于环境对传染病影响的一个会议的内容。
概述本次会议演讲所依据的文献。
演讲中使用的参考文献是由演讲者提供的。还从 PubMed 中使用演讲中的关键词获得了其他参考文献。
北海道纵向儿童研究发现，儿童早期接触化学物质，如持久性有机污染物和全氟/多氟化合物，与一系列免疫结果有关，如脐血 IgE 降低、中耳炎、喘息、感染风险增加和食物过敏风险增加。流行病学证据表明，在世界许多地区，暴露于空气质量差与新冠肺炎的严重程度和死亡率增加有关。大多数研究表明，长期暴露的影响比急性暴露更为显著。空气污染的成分，如一种新发现的称为环境持久性自由基的燃烧产物，会在暴露个体中引起氧化应激。易发生氧化应激的个体因空气质量差而导致不良健康后果的风险增加。
