Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Global Clinical Operations, Elekta Ltd, Crawley, West Sussex, UK.
Med Phys. 2023 Feb;50(2):1132-1148. doi: 10.1002/mp.16082. Epub 2022 Nov 22.
In Magnetic Resonance-Linac (MR-Linac) dosimetry formalisms, a new correction factor, k , has been introduced to account for corresponding changes to detector readings under the beam quality, Q, and the presence of magnetic field, B.
This study aims to develop and implement a Monte Carlo (MC)-based framework for the determination of k correction factors for a series of ionization chambers utilized for dosimetry protocols and dosimetric quality assurance checks in clinical 1.5 T MR-Linacs. Their dependencies on irradiation setup conditions are also investigated. Moreover, to evaluate the suitability of solid phantoms for dosimetry checks and end-to-end tests, changes to the detector readings due to the presence of small asymmetrical air gaps around the detector's tip are quantified.
Phase space files for three irradiation fields of the ELEKTA Unity 1.5 T/7 MV flattening-filter-free MR-Linac were provided by the manufacturer and used as source models throughout this study. Twelve ionization chambers (three farmer-type and nine small-cavity detectors, from three manufacturers) were modeled (including their dead volume) using the EGSnrc MC code package. k values were calculated for the 10 × 10 cm irradiation field and for four cardinal orientations of the detectors' axes with respect to the 1.5 T magnetic field. Potential dependencies of k values with respect to field size, depth, and phantom material were investigated by performing additional simulations. Changes to the detectors' readings due to the presence of small asymmetrical air gaps (0.1 up to 1 mm) around the chambers' sensitive volume in an RW3 solid phantom were quantified for three small-cavity chambers and two orientations.
For both parallel (to the magnetic field) orientations, k values were found close to unity. The maximum correction needed was 1.1%. For each detector studied, the k values calculated for the two parallel orientations agreed within uncertainties. Larger corrections (up to 5%) were calculated when the detectors were oriented perpendicularly to the magnetic field. Results were compared with corresponding ones found in the literature, wherever available. No considerable dependence of k with respect to field size (down to 3 × 3 cm ), depth, or phantom material was noticed, for the detectors investigated. As compared to the perpendicular one, in the parallel to the magnetic field orientation, the air gap effect is minimized but is still considerable even for the smallest air gap considered (0.1 mm).
For the 10 × 10 cm field, magnetic field correction factors for 12 ionization chambers and four orientations were determined. For each detector, the k value may be also applied for dosimetry procedures under different irradiation parameters provided that the orientation is taken into account. Moreover, if solid phantoms are used, even the smallest asymmetrical air gap may still bias small-cavity chamber response. This work substantially expands the availability and applicability of k correction factors that are detector- and orientation-specific, enabling more options in MR-Linac dosimetry checks, end-to-end tests, and quality assurance protocols.
在磁共振直线加速器(MR-Linac)剂量学形式中,引入了一个新的校正因子 k,以解释在束质 Q 和磁场 B 下探测器读数的相应变化。
本研究旨在开发和实施一种基于蒙特卡罗(MC)的框架,用于确定一系列电离室的 k 校正因子,这些电离室用于临床 1.5T MR-Linac 中的剂量学协议和剂量学质量保证检查。还研究了它们对辐照设置条件的依赖性。此外,为了评估固体体模在剂量学检查和端到端测试中的适用性,量化了由于探测器尖端周围存在小的不对称空气间隙而导致的探测器读数的变化。
制造商提供了三个 ELEKTA Unity 1.5T/7MV 无均整滤波器 MR-Linac 的照射场的相空间文件,并在整个研究中用作源模型。使用 EGSnrc MC 代码包对三个制造商的三个农房型和九个小腔探测器(包括其死体积)进行建模。为 10×10cm 照射场和探测器轴相对于 1.5T 磁场的四个方位计算了 k 值。通过进行额外的模拟,研究了 k 值与场大小、深度和体模材料的潜在依赖性。在 RW3 固体体模中,量化了三个小腔室和两个方位下,探测器敏感体积周围存在小的不对称空气间隙(0.1 至 1mm)时探测器读数的变化。
对于平行(与磁场平行)方向,发现 k 值接近 1。需要的最大校正值为 1.1%。对于研究的每个探测器,两个平行方向计算的 k 值在不确定度范围内一致。当探测器垂直于磁场时,计算出的校正值更大(高达 5%)。将结果与文献中可用的相应结果进行了比较。对于研究的探测器,没有发现 k 值与场大小(低至 3×3cm)、深度或体模材料有明显的依赖性。与垂直方向相比,在平行于磁场的方向上,空气间隙效应最小化,但即使考虑到最小的空气间隙(0.1mm),空气间隙效应仍然相当大。
为 10×10cm 场确定了 12 个电离室和四个方位的磁场校正因子。对于每个探测器,只要考虑到方位,k 值也可用于不同辐照参数下的剂量学程序。此外,如果使用固体体模,即使是最小的不对称空气间隙也可能会使小腔室的响应产生偏差。这项工作大大扩展了与探测器和方位相关的 k 校正因子的可用性和适用性,为 MR-Linac 剂量学检查、端到端测试和质量保证协议提供了更多选择。