Koretskaia N G, Piruzian E S
Genetika. 1978 Nov;14(11):1908-12.
Escherichia coli strains with deletions in att lambda region were obtained. The comparison of the extent of deletions with the sensitivity of the corresponding mutant clones to phage Mu showed that the gene controlling the sensitivity of E. coli K-12 to the phage Mu is located in nad A-gal region of the bacterial chromosome. It is shown that the resistance of E. coli strains which had lost the region of bacterial chromosome between nad A gene and genes of gal-operon have adsorption character. Deletion of the nad A-gal region does not affect the adsorption of other phages (lambda, P1 and T4). Thus, the gene, located in this region, is responsible for the specific adsorption of the phage Mu.
获得了在λ噬菌体附着区域存在缺失的大肠杆菌菌株。将缺失程度与相应突变克隆对噬菌体Mu的敏感性进行比较,结果表明,控制大肠杆菌K-12对噬菌体Mu敏感性的基因位于细菌染色体的nad A-半乳糖区域。结果表明,缺失了nad A基因与半乳糖操纵子基因之间细菌染色体区域的大肠杆菌菌株具有吸附特性。nad A-半乳糖区域的缺失不影响其他噬菌体(λ噬菌体、P1噬菌体和T4噬菌体)的吸附。因此,位于该区域的基因负责噬菌体Mu的特异性吸附。