Yunita Sendi Lia, Yang Hui-Wen, Chen Yi-Chun, Kao Li-Ting, Lu Yi-Zi, Wen Yuan-Liang, To Sheng-Yin, Huang Ya-Li
Pharmacy Department, Faculty of Health Science, University of Muhammadiyah Malang, Malang, Indonesia.
Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.
Front Pharmacol. 2022 Oct 24;13:1019303. doi: 10.3389/fphar.2022.1019303. eCollection 2022.
Antimicrobial resistance is a public health problem that threatens the efficacy of antibiotics. Incorrect knowledge of antibiotics may lead to their inappropriate use, hinder their effectiveness, and cause antibiotic resistance. Population-based educational campaigns have been found to have either mixed or no effect on improving knowledge and appropriate antibiotic practices, suggesting the need for more targeted approaches in tailoring education for specific subpopulations. Women are the primary caregivers of their families and are more willing to contact healthcare providers. They had greater knowledge of antibiotics and better adherence to the completion of the antibiotic regimen. Therefore, they are suitable for prioritization in a campaign program. This study examined the knowledge and practices of female visitors to health centers in Malang, Indonesia with respect to antibiotic use. This cross-sectional study was conducted in Malang, Indonesia, in July and August 2018. Data were collected from 677 women. Multivariate logistic regression was performed to identify the potential factors associated with antibiotic knowledge, self-medication, and completion of antibiotic regimens. Overall, 82.7% of respondents were aware that antibiotics are used against bacteria, while 38.4% reported self-medication with antibiotics and 51.7% reported completing antibiotic regimens. Women with higher education, previous antibiotic use experience, and very easy accessibility to primary doctors were more likely to have high antibiotic knowledge than those with primary education, no antibiotic use in the previous year, and easy/other level of accessibility to primary doctors. Subjects residing in urban areas and with less accessibility to primary doctors were more likely to self-medicate with antibiotics. Additionally, the completion of antibiotic regimens was positively associated with access to a primary care doctor and high antibiotic knowledge. IF Policymakers tend to reduce inappropriate antibiotic use among women. Priority advocates are recommended for urban residents who have experiences of antibiotic use in the previous year. It is therefore important to increase their awareness, particularly regarding diseases against which antibiotics are effective, and activities such as unnecessary use of antibiotics in healthy animals, which may affect their overall effectiveness among humans. More communication channels should be included in the overall scheme to improve the public awareness and accessibility of health professionals.
抗菌药物耐药性是一个威胁抗生素疗效的公共卫生问题。对抗生素的错误认知可能导致其使用不当,削弱其有效性,并引发抗生素耐药性。基于人群的教育活动在提高知识水平和促进抗生素合理使用方面,效果不一或毫无成效,这表明需要采取更具针对性的方法,为特定亚人群量身定制教育内容。女性是家庭的主要照顾者,更愿意联系医疗服务提供者。她们对抗生素有更多了解,并且在完成抗生素疗程方面依从性更好。因此,她们适合在宣传项目中被列为优先对象。本研究调查了印度尼西亚马朗健康中心女性访客在抗生素使用方面的知识和行为。这项横断面研究于2018年7月和8月在印度尼西亚马朗进行。收集了677名女性的数据。进行多变量逻辑回归分析,以确定与抗生素知识、自我用药以及完成抗生素疗程相关的潜在因素。总体而言,82.7%的受访者知道抗生素用于对抗细菌,而38.4%的受访者报告曾自行使用抗生素,51.7%的受访者报告完成了抗生素疗程。与小学学历、前一年未使用过抗生素且看初级医生的便利性为一般/其他水平的女性相比,受过高等教育、有过抗生素使用经历且看初级医生非常方便的女性更有可能具备丰富的抗生素知识。居住在城市地区且看初级医生不太方便的受试者更有可能自行使用抗生素。此外,完成抗生素疗程与能够看初级保健医生以及具备丰富的抗生素知识呈正相关。如果政策制定者倾向于减少女性中抗生素的不当使用。建议将前一年有过抗生素使用经历的城市居民作为优先宣传对象。因此,重要的是提高他们的认识,特别是关于抗生素有效的疾病,以及诸如在健康动物中不必要使用抗生素等可能影响其在人类中整体有效性的活动。在整体方案中应纳入更多沟通渠道,以提高公众意识和医疗专业人员的可及性。