Schäflein Eva, Mertens Yoki Linn, Lejko Nena, Beutler Sarah, Sattel Heribert, Sack Martin
Department of Psychosomatic Medicine and Psychotherapy, University Hospital of Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Germany; and Department of Psychosomatic Medicine and Psychotherapy, Hospital rechts der Isar of the Technical University of Munich, Germany.
Department of Clinical Psychology and Experimental Psychopathology, University of Groningen, The Netherlands.
BJPsych Open. 2022 Nov 10;8(6):e196. doi: 10.1192/bjo.2022.593.
People suffering from chronic dissociation often experience stress and detachment during self-perception. We tested 18 people with dissociative disorders not otherwise specified (DDNOS; compared with a matched sample of 18 healthy controls) undergoing a stress-inducing facial mirror confrontation paradigm, and measured acute dissociation and frontal electroencephalography (measured with a four-channel system) per experimental condition (e.g. confrontation with negative cognition). Linear mixed models indicated a significant group×time×condition effect, with DDNOS group depicting less electroencephalography power than healthy controls at the beginning of mirror confrontation combined with negative and positive cognition. This discrepancy - most prominent in the negative condition - diminished in the second minute. Correlational analyses depicted a positive association between initial electroencephalography power and acute dissociation in the DDNOS group. These preliminary findings may indicate altered neural processing in DDNOS, but require further investigation with more precise electroencephalography measures.
患有慢性解离症的人在自我认知过程中常常会经历压力和超脱感。我们对18名未另行指定的解离性障碍患者（与18名健康对照者的匹配样本相比）进行了一项压力诱导面部镜子对峙范式测试，并在每个实验条件下（例如与负面认知对峙）测量了急性解离和额叶脑电图（使用四通道系统测量）。线性混合模型显示出显著的组×时间×条件效应，在镜子对峙开始时，结合负面和正面认知，未另行指定的解离性障碍组的脑电图功率低于健康对照组。这种差异——在负面条件下最为明显——在第二分钟时减小。相关性分析表明，未另行指定的解离性障碍组中，初始脑电图功率与急性解离之间存在正相关。这些初步发现可能表明未另行指定的解离性障碍中神经处理过程发生了改变，但需要使用更精确的脑电图测量方法进行进一步研究。
