Kim Min Hyun, Park Sanghee, Yi Nari, Kang Bobae, Park In Ja
Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Vital Statistics Division, Statistics Korea, Daejeon, Korea.
Ann Coloproctol. 2022 Oct;38(5):343-352. doi: 10.3393/ac.2022.00535.0076. Epub 2022 Oct 28.
Korea has implemented an early screening for colorectal cancer since 2004. However, it is not known whether this has translated into improved survival over the years.
We acquired colorectal cancer mortality data from the Cause of Death Statistics in Korea from 2000 to 2020. We characterized the data into year of death, cancer-specific loci, and age group. We analyzed age-standardized mortality rates (ASMR) according to year of death, age group, and primary location to find trends in colorectal cancer mortality over a 20-year period.
The crude mortality rate of colorectal cancer increased from 8.78 per 100,000 in 2000 to 17.27 per 100,000 in 2020. The second decade was slower in increments compared to the first decade. ASMR showed a decrease over the second decade after an initial increase in the first decade. The decrease was primarily from the lowering of ASMR for rectosigmoid cancers. Age group analysis showed a lowering of ASMR mainly in the 45-59-year, 60-74-year, and ≥ 75-year age groups; however, 0-29-year and 30-44-year age groups showed generally unchanged ASMR over the total period.
After a brief incline of age-specific mortality of colorectal cancers during the early 2000s, colorectal cancer mortality has gradually been decreasing in the past decade. This was mainly due to decreased mortalities in rectosigmoid colon cancers especially in the age groups that were the target of early screening.
韩国自2004年起实施结直肠癌早期筛查。然而，多年来这种筛查是否转化为生存率的提高尚不清楚。
我们从韩国2000年至2020年的死因统计中获取了结直肠癌死亡率数据。我们将数据按死亡年份、癌症特定部位和年龄组进行分类。我们根据死亡年份、年龄组和原发部位分析年龄标准化死亡率（ASMR），以发现20年期间结直肠癌死亡率的趋势。
结直肠癌的粗死亡率从2000年的每10万人8.78例增加到2020年的每10万人17.27例。与第一个十年相比，第二个十年的增长速度较慢。ASMR在第一个十年最初上升后，在第二个十年呈下降趋势。下降主要是由于直肠乙状结肠癌的ASMR降低。年龄组分析显示，ASMR下降主要发生在45 - 59岁、60 - 74岁和≥75岁年龄组；然而，0 - 29岁和30 - 44岁年龄组在整个期间的ASMR总体保持不变。
在21世纪初结直肠癌年龄特异性死亡率短暂上升后，过去十年结直肠癌死亡率逐渐下降。这主要是由于直肠乙状结肠癌死亡率下降，尤其是在早期筛查目标年龄组中。
