Kolics Balázs, Kolics Éva, Solti Izabella, Bacsi Zsuzsanna, Taller János, Specziár András, Mátyás Kinga
Festetics Bioinnovation Group, Institute of Genetics and Biotechnology, Georgikon Campus, Hungarian University of Agriculture and Life Sciences, H-8360 Keszthely, Hungary.
Institute of Agricultural and Food Economics, Georgikon Campus, Hungarian University of Agriculture and Life Sciences, H-8360 Keszthely, Hungary.
Insects. 2022 Nov 1;13(11):1005. doi: 10.3390/insects13111005.
The poultry red mite () is the main pest of poultry, causing severe problems by being a vector of several animal and human pathogens. The number of miticides is few, and their efficacy in practice implies problems of residues and resistance; therefore, the demand for a new and safe agent is constant. The present publication investigated the effectiveness of lithium chloride under in vitro conditions on poultry red mites. This chemical currently appears to be one of the most promising alternatives to study amongst potential applicants to treat varroosis, a fatal disease of honey bees. In Experiment I, the previously used experimental doses (5.52 M, 2.76 M, 1.38 M) on mites confirmed their in vitro activity on the poultry red mite. Three event times (uncontrolled movement, immobilisation and death) were recorded to base the response to treatment for each concentration. In Experiment II, the LD 50 value was calculated, i.e., the value at which 50% of the mites were killed by the treatment. This Experiment showed that the LD50 of lithium chloride = 0.265 M in the poultry red mite. It is to note that the study remained restricted to in vitro confirmation of lithium chloride's effectiveness on the parasite. Thus, further extensive studies are needed to decide whether it has any relevance in practice against , and also to assess potential residue problems that could affect poultry products.
鸡皮刺螨是家禽的主要害虫，作为多种动物和人类病原体的传播媒介，会引发严重问题。杀螨剂的种类较少，且其在实际应用中的效果存在残留和抗性问题；因此，对新型安全药剂的需求一直存在。本出版物研究了氯化锂在体外条件下对鸡皮刺螨的有效性。这种化学物质目前似乎是在治疗蜜蜂致命疾病——瓦螨病的潜在候选物中最有前景的研究替代品之一。在实验I中，先前用于螨类的实验剂量（5.52 M、2.76 M、1.38 M）证实了其对鸡皮刺螨的体外活性。记录了三个事件时间（不受控制的运动、固定和死亡），以确定每种浓度下对处理的反应。在实验II中，计算了半数致死剂量（LD50）值，即处理导致50%的螨死亡时的值。该实验表明，氯化锂对鸡皮刺螨的LD50 = 0.265 M。需要注意的是，该研究仅限于体外证实氯化锂对该寄生虫的有效性。因此，需要进一步进行广泛研究，以确定其在实际中对鸡皮刺螨是否有任何相关性，同时评估可能影响家禽产品的潜在残留问题。
