Alapati Akhila, Cameron Nathaniel, Gratton Sean, Stahl Erin, Champion Mary
University of Kansas Medical Center, Department of Ophthalmology, 7400 State Line Road, Prairie Village, KS, 66208, USA.
Children's Mercy Hospital, Kansas City Missouri Department of Pediatric Ophthalmology, 2401 Gillham Road, Kansas City, MO, 64108, USA.
J Ophthalmic Inflamm Infect. 2022 Nov 10;12(1):38. doi: 10.1186/s12348-022-00316-z.
To report a case of frosted branch angiitis presenting in a pediatric patient with unremarkable laboratory work-up apart from SARS-CoV-2 IgG antibodies.
Less than four weeks after a SARS-CoV-2 infection, a 10 year-old female presented to the emergency department with severe headache and intermittent fevers. During her hospital admission, the ophthalmology service was consulted for blurry vision. Subsequent eye examination revealed frosted branch angiitis. The patient initially received intravenous corticosteroids but was escalated to plasmapheresis to achieve resolution of her symptoms. Outpatient maintenance therapy consisted of an oral Prednisone taper and Infliximab infusion.
This case represents a unique ocular manifestation of COVID-19, as recent SARS-CoV-2 was the sole identifiable cause of the patient's frosted branch angiitis. Additionally, this patient required plasmapheresis to control disease progression.
报告一例小儿霜样树枝状视网膜血管炎病例，该患儿除SARS-CoV-2 IgG抗体外，实验室检查无异常。
一名10岁女性在感染SARS-CoV-2后不到四周，因严重头痛和间歇性发热前往急诊科就诊。住院期间，因视力模糊咨询了眼科。随后的眼部检查发现了霜样树枝状视网膜血管炎。患者最初接受静脉注射皮质类固醇治疗，但升级为血浆置换以缓解症状。门诊维持治疗包括口服泼尼松逐渐减量和英夫利昔单抗输注。
该病例代表了COVID-19独特的眼部表现，因为近期感染的SARS-CoV-2是该患者霜样树枝状视网膜血管炎唯一可识别的病因。此外，该患者需要进行血浆置换以控制疾病进展。
