Pellegrino Carmen, Patti Giulia, Camporeale Michele, Belati Alessandra, Novara Roberta, Papagni Roberta, Frallonardo Luisa, Diella Lucia, Guido Giacomo, De Vita Elda, Totaro Valentina, Segala Francesco Vladimiro, Veronese Nicola, Cotugno Sergio, Bavaro Davide Fiore, Putoto Giovanni, Bevilacqua Nazario, Castellani Chiara, Nicastri Emanuele, Saracino Annalisa, Di Gennaro Francesco
Department of Biomedical Sciences and Human Oncology, Clinic of Infectious Diseases, University of Bari, 70121 Bari, Italy.
Department of Internal Medicine and Geriatrics, University of Palermo Geriatric Unit, 90121 Palermo, Italy.
Trop Med Infect Dis. 2022 Nov 10;7(11):366. doi: 10.3390/tropicalmed7110366.
Dracunculiasis, also known as Guinea worm disease (GWD), is a neglected tropical disease (NTD) caused by a parasite (). In the past, dracunculiasis was known as "the disease of the empty granary" because of the difficulties patients had in going to work in fields or to school when affected by this disease. In tropical areas, the condition has been widespread in economically disadvantaged communities, and has been associated with reduced economic status and low levels of education.
we searched PubMed, Scopus, Google Scholar, EMBASE, Cochrane Library, and WHO websites for literature addressing dracunculiasis published in the last 50 years.
by development and optimization of multi-layered control measures, transmission by the vector has been interrupted, but there are foci in several African countries with a high risk of compromising the results obtained in the control of this neglected disease.
this review features state-of-the-art data on the infection prevalence, geographical distribution, diagnostics, parasite-host interactions, and the pathology of dracunculiasis. Also described are the current state and future perspectives for vector control and elimination strategies.
麦地那龙线虫病，也称为几内亚蠕虫病（GWD），是一种由寄生虫引起的被忽视的热带病（NTD）。过去，麦地那龙线虫病被称为“空粮仓病”，因为患者感染此病后难以去田间劳作或上学。在热带地区，这种疾病在经济弱势社区广泛传播，并与经济地位下降和教育水平低有关。
我们在PubMed、Scopus、谷歌学术、EMBASE、Cochrane图书馆和世界卫生组织网站上搜索了过去50年发表的关于麦地那龙线虫病的文献。
通过制定和优化多层控制措施，已阻断了病媒传播，但在几个非洲国家仍存在病灶，这些病灶有破坏在控制这种被忽视疾病方面所取得成果的高风险。
本综述介绍了有关麦地那龙线虫病感染流行率、地理分布、诊断、寄生虫与宿主相互作用以及病理学的最新数据。还描述了病媒控制和消除策略的现状及未来前景。
