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低收入和中等收入国家的神经囊尾蚴病:来自乌干达奥亚姆区的诊断挑战

Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda.

作者信息

Segala Francesco Vladimiro, De Vita Elda, Amone James, Ongaro Daniel, Nassali Ritah, Oceng Bonny, Okori Samuel, Putoto Giovanni, Lochoro Peter, Ictho Jerry, Fantoni Massimo, Saracino Annalisa, Di Gennaro Francesco

机构信息

Clinic of Infectious Diseases, Catholic University of the Sacred Heart, 00168 Rome, Italy.

Department of Biomedical Sciences and Human Oncology, Clinic of Infectious Diseases, University of Bari, 70123 Bari, Italy.

出版信息

Infect Dis Rep. 2022 Jul 1;14(4):505-508. doi: 10.3390/idr14040054.

DOI:10.3390/idr14040054
PMID:35893473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9326654/
Abstract

BACKGROUND

In countries where is endemic, neurocysticercosis (NCC) is the leading identified cause of seizures, accounting for nearly 30% of all epilepsy cases and up to 2.8 million of Disability Adjusted Life Years. Diagnosis of this condition, however, is strictly reliant on either MRI or CT scan, which are poorly available in low- and middle-income countries (LMICs), creating challenges for proper case management and the acquisition of precise neuroepidemiologic data that may guide program and policy development.

METHODS

Here, we report the case of a 73-year-old woman admitted in a rural hospital in Northern Uganda, who presented with seizures and a progressive inability to walk. She was then diagnosed with NCC after a brain CT scan.

CONCLUSIONS

This case study represents a rare example of the detection of NCC in a rural district hospital, thus suggesting the potential feasibility of a CT-scan guided diagnostic approach in low resource settings.

摘要

背景

在囊尾蚴病流行的国家,神经囊尾蚴病(NCC)是已确定的癫痫发作的主要病因,占所有癫痫病例的近30%,导致多达280万个伤残调整生命年。然而,这种疾病的诊断严格依赖于MRI或CT扫描,而在低收入和中等收入国家(LMICs),这些设备的可及性很差,这给妥善的病例管理以及获取可能指导项目和政策制定的精确神经流行病学数据带来了挑战。

方法

在此,我们报告一例73岁女性患者的病例,该患者入住乌干达北部一家乡村医院,出现癫痫发作且逐渐无法行走。经脑部CT扫描后,她被诊断为神经囊尾蚴病。

结论

本病例研究是在农村地区医院检测到神经囊尾蚴病的罕见案例,因此表明在资源匮乏地区采用CT扫描引导的诊断方法具有潜在可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/9326654/fae38535b163/idr-14-00054-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/9326654/fae38535b163/idr-14-00054-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/9326654/fae38535b163/idr-14-00054-g001.jpg

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