以色列军事基地的猫中 SARS-CoV-2 的血清学检出率较低。
Low serological rate of SARS-CoV-2 in cats from military bases in Israel.
机构信息
Preventive medicine branch, Medical Corps, Israel Defense Forces, Tel Hashomer Camp, 5510802, Qriat Ono, Israel.
Preventive medicine branch, Medical Corps, Israel Defense Forces, Tel Hashomer Camp, 5510802, Qriat Ono, Israel.
出版信息
Comp Immunol Microbiol Infect Dis. 2022 Nov-Dec;90-91:101905. doi: 10.1016/j.cimid.2022.101905. Epub 2022 Nov 3.
Domestic cats are susceptible to SARS-CoV-2 infection and can transmit the virus to other felines. A high number of COVID-19 human cases within the military personnel and a high density of stray cats living close to soldiers raised the need to perform active animal surveillance. We validated a novel quantitative serological microarray for use in cats, that enables simultaneous detection of IgG and IgM responses; in addition, molecular genetic SARS-CoV-2 detection was performed. Three out of 131 cats analyzed, showed IgG antibodies against SARS-CoV-2 RBD and S2P (2.3 %). None of cats were positive for SARS-CoV-2 RNA by RT-PCR. SARS-CoV-2 infection rate in soldiers ranged from 4.7 % to 16 % (average rate=8.9 %). Further investigations on a larger cohort are necessary, in the light of the emerging new viral variants in other animal species and in humans.
家猫易感染 SARS-CoV-2 病毒，并可将病毒传播给其他猫科动物。在军人中有大量 COVID-19 病例，且有大量流浪猫生活在士兵附近，这引发了对动物进行主动监测的必要性。我们验证了一种新的用于猫的定量血清微阵列，该微阵列可同时检测 IgG 和 IgM 反应；此外，还进行了 SARS-CoV-2 的分子遗传检测。在分析的 131 只猫中，有 3 只猫的 IgG 抗体对 SARS-CoV-2 的 RBD 和 S2P 呈阳性（2.3%）。没有猫的 RT-PCR 检测到 SARS-CoV-2 RNA 呈阳性。通过 RT-PCR 检测，士兵中的 SARS-CoV-2 感染率在 4.7%到 16%之间（平均感染率为 8.9%）。鉴于其他动物物种和人类中出现的新病毒变异，有必要对更大的队列进行进一步研究。
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