身体活动和身体功能在体重指数与健康相关生活质量之间的关联中的中介作用：一项基于人群的老年人研究。
The Mediating Role of Physical Activity and Physical Function in the Association between Body Mass Index and Health-Related Quality of Life: A Population-Based Study with Older Adults.
机构信息
Department of Physical Education, Federal University of Vale do São Francisco, Petrolina 56304-917, PE, Brazil.
Department of Physical Education and Sport, University of Madeira, 9020-105 Funchal, Portugal.
出版信息
Int J Environ Res Public Health. 2022 Oct 22;19(21):13718. doi: 10.3390/ijerph192113718.
This study aimed (1) to investigate the association between body mass index (BMI), physical activity (PA), and physical function (PF) with health-related quality of life (HRQoL), and (2) to examine in-depth whether PA and PF mediate the relationship between BMI and HRQoL in older adults. We investigated 802 individuals (mean age 69.8 ± 5.6 years), residents of the Autonomous Region of Madeira, Portugal. Harmol and PA were assessed using the SF-36 and Baecke questionnaires, respectively, and PF by the Senior Fitness Test. The prevalence of overweight was 71.3%, 26.5% for normal weight, and 2.1% for underweight. We verified a small correlation between age and sex with BMI, PA, PF, and medium borderline with HRQoL. After adjusting for covariates (i.e., sex, age, comorbidities), the multivariate regression analysis indicated a 93.1% chance of improvement in HRQoL for low BMI, while PA and PF revealed a chance of increasing HRQoL by 91.8% and 60.0%, respectively. According to the serial mediation pathway, PA and PF partially mediated the association between BMI and HRQoL by 32.3% and 81.5%, respectively. The total variance of the model was 90%. It was concluded that BMI can negatively affect HRQoL. On the other hand, PA and PF are able to increase HRQoL levels during the aging process.
本研究旨在
(1) 探讨身体质量指数 (BMI)、身体活动 (PA) 和身体功能 (PF) 与健康相关生活质量 (HRQoL) 的关联；(2) 深入研究 PA 和 PF 是否在老年人 BMI 和 HRQoL 之间起中介作用。我们调查了 802 名个体（平均年龄 69.8±5.6 岁），他们是葡萄牙马德拉自治区的居民。使用 SF-36 和 Baecke 问卷评估 Harmol 和 PA，使用 Senior Fitness Test 评估 PF。超重的患病率为 71.3%，正常体重的患病率为 26.5%，体重不足的患病率为 2.1%。我们发现年龄和性别与 BMI、PA、PF 和 HRQoL 之间存在中等边界相关，而与 BMI、PA、PF 和 HRQoL 之间存在中等边界相关。在调整协变量（即性别、年龄、合并症）后，多元回归分析表明，BMI 低时 HRQoL 改善的可能性为 93.1%，而 PA 和 PF 则分别使 HRQoL 增加的可能性提高了 91.8%和 60.0%。根据串联中介途径，PA 和 PF 分别部分介导了 BMI 和 HRQoL 之间的关联，占比为 32.3%和 81.5%。模型的总方差为 90%。结论是 BMI 会对 HRQoL 产生负面影响。另一方面，PA 和 PF 能够在衰老过程中提高 HRQoL 水平。
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