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不透射线的晶体、非晶体和纳米结构生物陶瓷

Radiopaque Crystalline, Non-Crystalline and Nanostructured Bioceramics.

作者信息

Montazerian Maziar, Gonçalves Geovanna V S, Barreto Maria E V, Lima Eunice P N, Cerqueira Glauber R C, Sousa Julyana A, Malek Khachatourian Adrine, Souza Mairly K S, Silva Suédina M L, Fook Marcus V L, Baino Francesco

机构信息

Northeastern Laboratory for Evaluation and Development of Biomaterials (CERTBIO), Federal University of Campina Grande, Campina Grande 58429-900, PB, Brazil.

Department of Materials Science and Engineering, Sharif University of Technology, Tehran 11155-1639, Iran.

出版信息

Materials (Basel). 2022 Oct 25;15(21):7477. doi: 10.3390/ma15217477.

DOI:10.3390/ma15217477
PMID:36363085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9656675/
Abstract

Radiopacity is sometimes an essential characteristic of biomaterials that can help clinicians perform follow-ups during pre- and post-interventional radiological imaging. Due to their chemical composition and structure, most bioceramics are inherently radiopaque but can still be doped/mixed with radiopacifiers to increase their visualization during or after medical procedures. The radiopacifiers are frequently heavy elements of the periodic table, such as Bi, Zr, Sr, Ba, Ta, Zn, Y, etc., or their relevant compounds that can confer enhanced radiopacity. Radiopaque bioceramics are also intriguing additives for biopolymers and hybrids, which are extensively researched and developed nowadays for various biomedical setups. The present work aims to provide an overview of radiopaque bioceramics, specifically crystalline, non-crystalline (glassy), and nanostructured bioceramics designed for applications in orthopedics, dentistry, and cancer therapy. Furthermore, the modification of the chemical, physical, and biological properties of parent ceramics/biopolymers due to the addition of radiopacifiers is critically discussed. We also point out future research lacunas in this exciting field that bioceramists can explore further.

摘要

射线不透性有时是生物材料的一个基本特性，它有助于临床医生在介入前和介入后的放射成像过程中进行随访。由于其化学成分和结构，大多数生物陶瓷本质上是射线不透的，但仍可与射线不透剂掺杂/混合，以在医疗程序期间或之后增强其可视性。射线不透剂通常是元素周期表中的重元素，如铋（Bi）、锆（Zr）、锶（Sr）、钡（Ba）、钽（Ta）、锌（Zn）、钇（Y）等，或者是能增强射线不透性的相关化合物。射线不透的生物陶瓷也是生物聚合物和复合材料中有趣的添加剂，如今针对各种生物医学应用对其进行了广泛的研究和开发。本工作旨在概述射线不透的生物陶瓷，特别是为骨科、牙科和癌症治疗应用设计的结晶、非晶（玻璃态）和纳米结构生物陶瓷。此外，还将严格讨论由于添加射线不透剂而导致的母体陶瓷/生物聚合物的化学、物理和生物学性质的改变。我们还指出了这个令人兴奋的领域中生物陶瓷学家可以进一步探索的未来研究空白。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/48ce10375aaf/materials-15-07477-g012.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/d0d3914d9934/materials-15-07477-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/963eda31bbb0/materials-15-07477-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/f67ba966614a/materials-15-07477-g008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/48ce10375aaf/materials-15-07477-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/73616692119f/materials-15-07477-g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/83bff5c29163/materials-15-07477-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/61f0fe8ae35b/materials-15-07477-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/dee2c92a990e/materials-15-07477-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/4fe2c5fee6bb/materials-15-07477-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/d0d3914d9934/materials-15-07477-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/963eda31bbb0/materials-15-07477-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/f67ba966614a/materials-15-07477-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/2c4c3b5e82aa/materials-15-07477-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/174f97829ba6/materials-15-07477-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/826864f3fc1b/materials-15-07477-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638c/9656675/48ce10375aaf/materials-15-07477-g012.jpg

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J Funct Biomater. 2022 Dec 31;14(1):23. doi: 10.3390/jfb14010023.
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