College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Nutrients. 2022 Nov 3;14(21):4654. doi: 10.3390/nu14214654.
Background: Few studies have combined the degree and duration of abdominal obesity into a waist circumference-years construct for analysis. The purpose of this study was to investigate the effect of waist circumference-years on the incidence of type 2 diabetes. Methods: A total of 6616 adults from the China Health and Nutrition Survey (CHNS) were enrolled in this study from 1997. The waist circumference-years construct was represented as the sum of the upper and lower area between the waist circumference baseline (men: ≥90 cm, women: ≥85 cm) and the waist circumference line. The correlations in the study were analyzed using logistic regression. Results: The incidence of type 2 diabetes increased with increasing waist circumference-years, with an adjusted risk increase of 38% (95% CI: 31−47%) for each additional 50 waist circumference-years, and this rate was similar across gender and age groups. The area under the curve of waist circumference-years (0.743) was greatest in the receiver operating characteristic curve (ROC) analysis compared to baseline waist circumference (0.731) and the waist-height ratio (0.728) (p < 0.05). Conclusion: The waist circumference-years construct is closely associated with an increased risk of type 2 diabetes and may be a stronger predictor of type 2 diabetes risk than baseline waist circumference or the waist-height ratio.
很少有研究将腹部肥胖的程度和持续时间综合到腰围年构建中进行分析。本研究旨在探讨腰围年对 2 型糖尿病发病的影响。
本研究共纳入 1997 年中国健康与营养调查（CHNS）中的 6616 名成年人。腰围年构建表示腰围基线（男性：≥90cm，女性：≥85cm）和腰围线之间的上下区域的总和。采用逻辑回归分析研究中的相关性。
随着腰围年的增加，2 型糖尿病的发病率呈上升趋势，每增加 50 个腰围年，调整后的风险增加 38%（95%CI：31-47%），且这种趋势在性别和年龄组之间相似。在受试者工作特征曲线（ROC）分析中，腰围年的曲线下面积（0.743）大于基线腰围（0.731）和腰高比（0.728）（p<0.05）。
腰围年构建与 2 型糖尿病发病风险增加密切相关，其可能是比基线腰围或腰高比更强的 2 型糖尿病风险预测指标。
