Department of Epidemiology and Medical Statistics, School of Public Health, Nantong University, No 9 Seyuan Road, Nantong, Jiangsu, 226019, China.
Nantong Chongchuan District Center for Disease Control and Prevention, Nantong, Jiangsu, 226000, China.
BMC Geriatr. 2022 Jan 3;22(1):20. doi: 10.1186/s12877-021-02713-w.
Obesity is associated with type 2 diabetes mellitus (T2DM). However, the obesity index that is most closely related to type 2 diabetes remains controversial. Therefore, the aim of this study was to compare the associations of five anthropometric indices (body mass index [BMI], body adiposity index, waist circumference [WC], waist-to-hip ratio, and waist-to-height ratio [WHtR]) with T2DM among Chinese adults divided into four groups according to sex and age.
A total of 4007 adult participants (1669 men and 2338 women) were included in the study. Odds ratios (ORs) and 95% confidence intervals were used with binary logistic regression models to estimate the risk of T2DM for each obesity index. Furthermore, we compared the area under the receiver operating characteristic curve (AUC) of each obesity index for the criterion of T2DM under the influence of risk factors.
WC had the highest OR (3.211 and 1.452) and AUC (0.783 and 0.614) in both age groups of men. However, WHtR (OR = 2.366, AUC = 0.771) and BMI (OR = 1.596, AUC = 0.647) were the optimal criteria for predicting T2DM among females in the 18-59 and ≥ 60 years age groups, respectively.
This study suggests that there is a positive association between obesity-related anthropometric indices and T2DM in different sex and age groups. WC appears to be the optimal anthropometric index for predicting T2DM in men. The optimal obesity indices related to T2DM were WHtR and BMI for women aged 18-59 and ≥ 60 years, respectively.
肥胖与 2 型糖尿病（T2DM）有关。然而，与 2 型糖尿病关系最密切的肥胖指数仍存在争议。因此，本研究旨在比较五种人体测量指数（体重指数[BMI]、体脂指数、腰围[WC]、腰臀比和腰高比[WHtR]）与按性别和年龄分为四组的中国成年人 T2DM 的相关性。
共纳入 4007 名成年参与者（男 1669 名，女 2338 名）。使用二项逻辑回归模型的比值比（OR）和 95%置信区间来估计每个肥胖指数与 T2DM 的风险。此外，我们比较了每个肥胖指数在危险因素影响下作为 T2DM 标准的接受者操作特征曲线（ROC）下面积（AUC）。
在男性的两个年龄组中，WC 的 OR（3.211 和 1.452）和 AUC（0.783 和 0.614）最高。然而，WHtR（OR=2.366，AUC=0.771）和 BMI（OR=1.596，AUC=0.647）是预测 18-59 岁和≥60 岁女性 T2DM 的最佳标准。
本研究表明，肥胖相关人体测量指数与不同性别和年龄组的 T2DM 之间存在正相关。WC 似乎是男性预测 T2DM 的最佳人体测量指数。对于 18-59 岁和≥60 岁的女性，与 T2DM 相关的最佳肥胖指数分别为 WHtR 和 BMI。
