Shafie Nur Juliani, Halim Najma Syahmin Abdul, Awoniyi Adedayo Michael, Zalipah Mohamed Nor, Md-Nor Shukor, Nazri Mohd Ulul Ilmie Ahmad, Costa Federico
Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, Kuala Nerus 21030, Terengganu, Malaysia.
Institute of Biology, Federal University of Bahia, Salvador 40170-115, Brazil.
Pathogens. 2022 Nov 5;11(11):1300. doi: 10.3390/pathogens11111300.
Leptospirosis is an important zoonotic disease that is transmitted worldwide through infected small mammals such as rodents. In Malaysia, there is a paucity of information on the animal reservoirs that are responsible for leptospirosis transmission, with only a few studies focusing on leptospirosis risk in recreational areas. Therefore, in this study we characterized the species composition and the prevalence of pathogenic spp. in non-volant small mammals of Hutan Lipur Sekayu, Terengganu. We performed ten trapping sessions totaling 3000 trappings between September 2019 and October 2020. Kidney samples from captured individuals were extracted for the PCR detection of pathogenic spp. Overall, we captured 45 individuals from 8 species (1.56% successful trapping effort), with 9 individuals testing positive for pathogenic , that is, a 20% (n = 9/45) prevalence rate. (n = 22) was the most dominant captured species and had the highest positive individual with pathogenic (44.4%, n = 4/9). Despite the low successful trapping effort in this study, the results show the high diversity of non-volant small mammals in Hutan Lipur Sekayu, and that they could also maintain and transmit pathogenic .
钩端螺旋体病是一种重要的人畜共患病,通过受感染的小型哺乳动物(如啮齿动物)在全球范围内传播。在马来西亚,关于导致钩端螺旋体病传播的动物宿主的信息匮乏,仅有少数研究关注休闲区域的钩端螺旋体病风险。因此,在本研究中,我们对登嘉楼州塞卡尤休闲林非飞行小型哺乳动物的物种组成和致病性钩端螺旋体的患病率进行了特征描述。我们在2019年9月至2020年10月期间进行了十次诱捕活动,总共进行了3000次诱捕。从捕获个体的肾脏样本中提取DNA,用于致病性钩端螺旋体的PCR检测。总体而言,我们从8个物种中捕获了45只个体(成功诱捕率为1.56%),其中9只个体的致病性钩端螺旋体检测呈阳性,即患病率为20%(n = 9/45)。黄毛鼠(n = 22)是捕获最多的物种,且致病性钩端螺旋体检测呈阳性的个体比例最高(44.4%,n = 4/9)。尽管本研究中的成功诱捕率较低,但结果显示塞卡尤休闲林非飞行小型哺乳动物具有高度多样性,并且它们也可能维持和传播致病性钩端螺旋体。