Siena Leonardo Maria, Isonne Claudia, Sciurti Antonio, De Blasiis Maria Roberta, Migliara Giuseppe, Marzuillo Carolina, De Vito Corrado, Villari Paolo, Baccolini Valentina
Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.
Vaccines (Basel). 2022 Oct 29;10(11):1832. doi: 10.3390/vaccines10111832.
Despite health literacy (HL) being recognized as a driver of health-promoting behavior, its influence on the vaccination decision-making process remains unclear. This study summarized current evidence on the association between HL and both intention to vaccinate and vaccination status. We searched PubMed, Scopus, and Web of Science, retrieving observational studies published until January 2022 that used HL-validated tools to investigate the above associations for any vaccine. Quality was assessed using the Newcastle-Ottawa scale. Twenty-one articles were included; of these, six investigated the intention to vaccinate and the remainder vaccination status. Articles on intention looked at SARS-CoV-2 vaccination using heterogeneous HL tools and were of high/fair quality. Vaccination status, mainly for influenza or pneumococcal vaccines, was explored using various HL tools; the quality was generally high. We found inconsistent results across and within vaccine types, with no clear conclusion for either vaccination intention or status. A weak but positive association was reported between a high HL level and influenza vaccination uptake for individuals aged more than 65 years. HL did not seem to significantly influence behavior towards vaccination. Differences in the methods used might explain these results. Further research is needed to investigate the role of HL in the vaccination decision-making process.
尽管健康素养（HL）被认为是促进健康行为的一个驱动因素，但其对疫苗接种决策过程的影响仍不明确。本研究总结了关于HL与疫苗接种意愿及疫苗接种状况之间关联的现有证据。我们检索了PubMed、Scopus和科学网，获取截至2022年1月发表的观察性研究，这些研究使用经过HL验证的工具来调查上述任何疫苗的关联。使用纽卡斯尔-渥太华量表评估质量。纳入了21篇文章；其中，6篇研究了疫苗接种意愿，其余研究了疫苗接种状况。关于意愿的文章使用了不同的HL工具研究了新冠病毒疫苗接种情况，质量为高/中等。疫苗接种状况主要针对流感或肺炎球菌疫苗，使用了各种HL工具进行探索；质量总体较高。我们在不同疫苗类型之间和内部都发现了不一致的结果，对于疫苗接种意愿或状况均无明确结论。据报告，65岁以上个体的高HL水平与流感疫苗接种率之间存在微弱但积极的关联。HL似乎并未显著影响疫苗接种行为。所用方法的差异可能解释了这些结果。需要进一步研究来调查HL在疫苗接种决策过程中的作用。
