Voigt Wieland, Trautwein Martin
Wieland Voigt, Medical Innovations and Management, Steinbeis University Berlin, Berlin.
Martin Trautwein, Senior Medical Advisor, Cognostics GmbH, Munich, Germany.
Curr Opin Oncol. 2023 Jan 1;35(1):68-77. doi: 10.1097/CCO.0000000000000916. Epub 2022 Nov 11.
Despite several efforts to enhance guideline adherence in cancer management, the rate of adherence remains often dissatisfactory in clinical routine. Clinical decision-support systems (CDSS) have been developed to support the management of cancer patients by providing evidence-based recommendations. In this review, we focus on both current evidence supporting the beneficial effects of CDSS on guideline adherence as well as technical and structural requirements for CDSS implementation in clinical routine.
Some studies have demonstrated a significant improvement of guideline adherence by CDSSs in oncologic diseases such as breast cancer, colon cancer, cervical cancer, prostate cancer, and hepatocellular carcinoma as well as in the management of cancer pain. However, most of these studies were rather small and designs rather simple. One reason for this limited evidence might be that CDSSs are only occasionally implemented in clinical routine. The main limitations for a broader implementation might lie in the currently existing clinical data infrastructures that do not sufficiently allow CDSS interoperability as well as in some CDSS tools themselves, if handling is hampered by poor usability.
In principle, CDSSs improve guideline adherence in clinical cancer management. However, there are some technical und structural obstacles to overcome to fully implement CDSSs in clinical routine.
尽管为提高癌症管理中指南的依从性付出了诸多努力,但在临床实践中,依从率往往仍不尽人意。临床决策支持系统(CDSS)已被开发出来,通过提供基于证据的建议来支持癌症患者的管理。在本综述中,我们既关注支持CDSS对指南依从性有益影响的当前证据,也关注CDSS在临床实践中实施的技术和结构要求。
一些研究表明,CDSS在乳腺癌、结肠癌、宫颈癌、前列腺癌和肝细胞癌等肿瘤疾病以及癌症疼痛管理中,能显著提高指南依从性。然而,这些研究大多规模较小且设计较为简单。证据有限的一个原因可能是CDSS只是偶尔在临床实践中实施。更广泛实施的主要限制可能在于当前现有的临床数据基础设施不足以实现CDSS的互操作性,以及一些CDSS工具本身,如果其易用性差导致操作受阻的话。
原则上,CDSS可提高临床癌症管理中的指南依从性。然而,要在临床实践中全面实施CDSS,还需克服一些技术和结构上的障碍。