Bigelow L B, Donnelly E P, Torrey E F, Lee C A
J Clin Psychiatry. 1979 Jun;40(6):258-61.
A previous study indicated that the Comprehension subtest of the Wechsler Adult Intelligence Scale (WAIS) might be a sensitive instrument for evaluating mental status in schizophrenic patients. To test this hypothesis, 3 groups of subjects were given the WAIS Comprehension subtest repeatedly at brief intervals. The results indicate that for a given individual (normal control or stable chronic schizophrenic), scores do not increase even with 4 consecutive weeks of testing. In contrast, a group of schizophrenic patients tested shortly after readmission and again after being established on neuroleptic medication showed a marked improvement in scores which, somewhat surprisingly, were not correlated with changes in global ratings of disordered thinking by the treating psychiatrist. This standardized test may offer a convenient objective technique for quantifying some aspects of thinking in schizophrenic patients.
先前的一项研究表明，韦氏成人智力量表（WAIS）的领悟分测验可能是评估精神分裂症患者精神状态的一种敏感工具。为了验证这一假设，对三组受试者在短时间间隔内反复进行WAIS领悟分测验。结果表明，对于特定个体（正常对照组或稳定的慢性精神分裂症患者），即使连续测试4周，分数也不会增加。相比之下，一组精神分裂症患者在重新入院后不久进行测试，在使用抗精神病药物治疗后再次测试，结果显示分数有显著提高，而令人惊讶的是，分数的提高与主治精神科医生对思维紊乱的整体评分变化无关。这种标准化测试可能为量化精神分裂症患者思维的某些方面提供一种便捷的客观技术。
