Pan Fan, He Peiyu, Qian Yongjun, Gao Hu, Chen Fei, Liu Haipeng, Zheng Dingchang
College of Electronics and Information Engineering, Sichuan University, Chengdu 610064, People's Republic of China.
Department of Cardiovascular Surgery, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, People's Republic of China.
Physiol Meas. 2022 Dec 1;43(11). doi: 10.1088/1361-6579/aca26d.
The oscillometric blood pressure (BP) measurement technique estimates BPs from analyzing the oscillometric cuff pressure waveform (oscillogram) envelope. The oscillogram envelope maximum is associated with physiological changes and influences BP measurement accuracy. We aim to quantitatively investigate the effect of BP and aging on the changes of oscillogram envelope maximum.Four hundred and sixty-two subjects (214 female, 248 male) were recruited. The cuff pressure was digitally recorded during linear cuff deflation to derive oscillogram envelopes and their maximums. Moderation analysis was performed to investigate whether the relationship between BP and envelope maximum was moderated by age. Subjects were divided into five age categories and three BP groups. The envelope maximums were compared between different BP and age categories to qualify their changes with increased BP and aging.Age has a significant moderating effect on the relationship between BP and envelope maximum ( < 0.05). The oscillogram envelope maximums increased significantly with increased BPs ( < 0.05 between each BP groups) and aging ( < 0.05 for > 60 years old groups in comparison with younger groups).This study experientially and theoretically concluded the BPs and aging are two important factors that influence the maximum value of the oscillogram envelope.
示波法血压测量技术通过分析示波袖带压力波形(示波图)包络来估算血压。示波图包络最大值与生理变化相关,并影响血压测量准确性。我们旨在定量研究血压和衰老对示波图包络最大值变化的影响。招募了462名受试者(214名女性,248名男性)。在袖带线性放气过程中对袖带压力进行数字记录,以得出示波图包络及其最大值。进行调节分析以研究血压与包络最大值之间的关系是否受年龄调节。受试者分为五个年龄组和三个血压组。比较不同血压和年龄组之间的包络最大值,以确定其随血压升高和衰老的变化情况。年龄对血压与包络最大值之间的关系具有显著的调节作用(<0.05)。示波图包络最大值随血压升高(各血压组之间<0.05)和衰老(60岁以上组与较年轻组相比<0.05)而显著增加。本研究通过实验和理论得出结论,血压和衰老都是影响示波图包络最大值的重要因素。